The beta-lactam biosynthesis genes for isopenicillin N epimerase and deacetoxycephalosporin C synthetase are expressed from a single transcript in Streptomyces clavuligerus.
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Molecular regulation of beta-lactam biosynthesis in filamentous fungiCloning and location of a gene governing lysine epsilon-aminotransferase, an enzyme initiating beta-lactam biosynthesis in Streptomyces spp.Investigation of the Streptomyces clavuligerus cephamycin C gene cluster and its regulation by the CcaR protein.Characterization of DNA-binding sequences for CcaR in the cephamycin-clavulanic acid supercluster of Streptomyces clavuligerus.Pyoverdine biosynthesis and secretion in Pseudomonas aeruginosa: implications for metal homeostasis.The enzymes of β-lactam biosynthesis.Homology of the NifS family of proteins to a new class of pyridoxal phosphate-dependent enzymes.Compilation and analysis of DNA sequences associated with apparent streptomycete promoters.Early cephamycin biosynthetic genes are expressed from a polycistronic transcript in Streptomyces clavuligerus.The nine genes of the Nocardia lactamdurans cephamycin cluster are transcribed into large mRNAs from three promoters, two of them located in a bidirectional promoter region.CcaR is an autoregulatory protein that binds to the ccaR and cefD-cmcI promoters of the cephamycin C-clavulanic acid cluster in Streptomyces clavuligerus.The bla gene of the cephamycin cluster of Streptomyces clavuligerus encodes a class A beta-lactamase of low enzymatic activity.Cloning and sequencing of the beta-lactam hydroxylase gene (cefF) from Streptomyces clavuligerus: gene duplication may have led to separate hydroxylase and expandase activities in the actinomycetes.Localization of the lysine epsilon-aminotransferase (lat) and delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase (pcbAB) genes from Streptomyces clavuligerus and production of lysine epsilon-aminotransferase activity in Escherichia coli.Proteome analysis of the penicillin producer Penicillium chrysogenum: characterization of protein changes during the industrial strain improvement.Engineering antibiotic producers to overcome the limitations of classical strain improvement programs.A novel epimerization system in fungal secondary metabolism involved in the conversion of isopenicillin N into penicillin N in Acremonium chrysogenum.Environmentally safe production of 7-aminodeacetoxycephalosporanic acid (7-ADCA) using recombinant strains of Acremonium chrysogenum.Roles of 2-oxoglutarate oxygenases and isopenicillin N synthase in β-lactam biosynthesis
P2860
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P2860
The beta-lactam biosynthesis genes for isopenicillin N epimerase and deacetoxycephalosporin C synthetase are expressed from a single transcript in Streptomyces clavuligerus.
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1990 nî lūn-bûn
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1990年の論文
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name
The beta-lactam biosynthesis g ...... in Streptomyces clavuligerus.
@en
type
label
The beta-lactam biosynthesis g ...... in Streptomyces clavuligerus.
@en
prefLabel
The beta-lactam biosynthesis g ...... in Streptomyces clavuligerus.
@en
P2093
P2860
P1476
The beta-lactam biosynthesis g ...... in Streptomyces clavuligerus.
@en
P2093
P2860
P304
P356
10.1128/JB.172.7.3952-3958.1990
P407
P577
1990-07-01T00:00:00Z