Telomerase inhibition potentiates the effects of genotoxic agents in breast and colorectal cancer cells in a cell cycle-specific manner.
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Telomerase as a Cancer Target. Development of New MoleculesIn vitro and ex vivo inhibition of human telomerase by anti-HIV nucleoside reverse transcriptase inhibitors (NRTIs) but not by non-NRTIsMicroRNA-18a attenuates DNA damage repair through suppressing the expression of ataxia telangiectasia mutated in colorectal cancerEffects of octreotide and insulin on colon cancer cellular proliferation and correlation with hTERT activityCorrelation of chromosomal instability, telomere length and telomere maintenance in microsatellite stable rectal cancer: a molecular subclass of rectal cancer.Telomerase expression and telomere length in breast cancer and their associations with adjuvant treatment and disease outcome.Telomerase regulates MYC-driven oncogenesis independent of its reverse transcriptase activity.Novel connections between DNA replication, telomere homeostasis, and the DNA damage response revealed by a genome-wide screen for TEL1/ATM interactions in Saccharomyces cerevisiae.Telomerase as a useful target in cancer fighting-the breast cancer case.Structure-function relationship and biogenesis regulation of the human telomerase holoenzyme.A combination of the telomerase inhibitor, BIBR1532, and paclitaxel synergistically inhibit cell proliferation in breast cancer cell lines.Telomerase reverse transcriptase expression protects transformed human cells against DNA-damaging agents, and increases tolerance to chromosomal instability.Temporal profiling of lapatinib-suppressed phosphorylation signals in EGFR/HER2 pathways.Telomerase promotes efficient cell cycle kinetics and confers growth advantage to telomerase-negative transformed human cells.Keratin 23 promotes telomerase reverse transcriptase expression and human colorectal cancer growth.Telomerase activity in breast cancer patients: association with poor prognosis and more aggressive phenotype.
P2860
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P2860
Telomerase inhibition potentiates the effects of genotoxic agents in breast and colorectal cancer cells in a cell cycle-specific manner.
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2010 nî lūn-bûn
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2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
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2010年學術文章
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2010年學術文章
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name
Telomerase inhibition potentia ...... a cell cycle-specific manner.
@en
type
label
Telomerase inhibition potentia ...... a cell cycle-specific manner.
@en
prefLabel
Telomerase inhibition potentia ...... a cell cycle-specific manner.
@en
P1433
P1476
Telomerase inhibition potentia ...... n a cell cycle-specific manner
@en
P2093
Helen B Fleisig
Raina A Tamakawa
P304
P356
10.1158/0008-5472.CAN-10-2227
P407
P50
P577
2010-09-13T00:00:00Z