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Telomerase RNA level limits telomere maintenance in X-linked dyskeratosis congenitaIn vitro and ex vivo inhibition of human telomerase by anti-HIV nucleoside reverse transcriptase inhibitors (NRTIs) but not by non-NRTIsThe telomerase reverse transcriptase regulates chromatin state and DNA damage responses.Telomere maintenance and disease.The accumulation and not the specific activity of telomerase ribonucleoprotein determines telomere maintenance deficiency in X-linked dyskeratosis congenita.Real-time and quantitative fluorescent live-cell imaging with quadruplex-specific red-edge probe (G4-REP).Telomerase as a clinical target: current strategies and potential applications.Direct visualization of both DNA and RNA quadruplexes in human cells via an uncommon spectroscopic methodStructure-function relationship and biogenesis regulation of the human telomerase holoenzyme.Telomerase inhibition potentiates the effects of genotoxic agents in breast and colorectal cancer cells in a cell cycle-specific manner.Human telomerase reverse transcriptase motifs required for elongation of a telomeric substrate.Investigation of chromosome X inactivation and clinical phenotypes in female carriers of DKC1 mutations.Visualization of RNA-Quadruplexes in Live Cells.Telomerase reverse transcriptase expression protects transformed human cells against DNA-damaging agents, and increases tolerance to chromosomal instability.Severity of X-linked dyskeratosis congenita (DKCX) cellular defects is not directly related to dyskerin (DKC1) activity in ribosomal RNA biogenesis or mRNA translation.Measuring cell cycle progression kinetics with metabolic labeling and flow cytometry.Subnuclear shuttling of human telomerase induced by transformation and DNA damage.Human aryl hydrocarbon receptor polymorphisms that result in loss of CYP1A1 induction.Quantification of Pseudouridine Levels in Cellular RNA Pools with a Modified HPLC-UV Assay.Cellular Detection of G-Quadruplexes by Optical Imaging Methods.Transcriptome-wide identification of transient RNA G-quadruplexes in human cellsTransient Telomerase Inhibition with Imetelstat Impacts DNA Damage Signals and Cell-Cycle KineticsFailure of Ah Receptor to Mediate Induction of Cytochromes P450 in the CYP1 Family in the Human Hepatoma Line SK-Hep-1Binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin to AH receptor in placentas from normal versus abnormal pregnancy outcomes
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description
hulumtuese
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Judy Wong
@ast
Judy Wong
@en
Judy Wong
@es
Judy Wong
@nl
Judy Wong
@sl
type
label
Judy Wong
@ast
Judy Wong
@en
Judy Wong
@es
Judy Wong
@nl
Judy Wong
@sl
prefLabel
Judy Wong
@ast
Judy Wong
@en
Judy Wong
@es
Judy Wong
@nl
Judy Wong
@sl
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P1153
34881133600
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P31
P496
0000-0001-5572-4143