Delta-opioid-receptor-mediated inhibition of adenylate cyclase is transduced specifically by the guanine-nucleotide-binding protein Gi2
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Analysis of the relative interactions between the alpha 2C10 adrenoceptor and the guanine-nucleotide-binding proteins G(o)1 alpha and Gi 2 alpha following co-expression of these polypeptides in rat 1 fibroblastsFunctional modulation of human delta opioid receptor by neuropeptide FF.Mechanisms of inhibition of insulin release.The alpha 2B adrenergic receptor of undifferentiated neuroblastoma x glioma hybrid NG108-15 cells, interacts directly with the guanine nucleotide binding protein, Gi2Opioid receptor signalling mechanisms.The G proteins of the G alpha i and G alpha q family couple the bradykinin receptor to the release of endothelium-derived relaxing factor.Differential capacities of the RGS1, RGS16 and RGS-GAIP regulators of G protein signaling to enhance alpha2A-adrenoreceptor agonist-stimulated GTPase activity of G(o1)alpha.Gonadotrophin-releasing hormone receptor agonist-mediated down-regulation of Gq alpha/G11 alpha (pertussis toxin-insensitive) G proteins in alpha T3-1 gonadotroph cells reflects increased G protein turnover but not alterations in mRNA levels.Transport of receptors, receptor signaling complexes and ion channels via neuropeptide-secretory vesiclesPost-transcriptional regulation of opioid receptors in the nervous system.Opioid peptides activate phospholipase D and protein kinase C-epsilon in chicken embryo neuron cultures.Go mediates the coupling of the mu opioid receptor to adenylyl cyclase in cloned neural cells and brain.Molecular Pharmacology of δ-Opioid Receptors.'Crosstalk': a pivotal role for protein kinase C in modulating relationships between signal transduction pathways.GRIN1 regulates micro-opioid receptor activities by tethering the receptor and G protein in the lipid raftEvidence from basic research for opioid combinations.The role of palmitoylation of the guanine nucleotide binding protein G11 alpha in defining interaction with the plasma membrane.Comparison of the signalling properties of the long and short isoforms of the rat thyrotropin-releasing-hormone receptor following expression in rat 1 fibroblastsBiochemical approaches to examine the specificity of interactions between receptors and guanine nuclotide binding proteins.Differential G-protein activation by alkaloid and peptide opioid agonists in the human neuroblastoma cell line SK-N-BE.Measurement of agonist-induced guanine nucleotide turnover by the G-protein Gi1alpha when constrained within an alpha2A-adrenoceptor-Gi1alpha fusion protein.The human delta opioid receptor activates G(i1)alpha more efficiently than G(o1)alpha.Changes in opioid receptor proteins during mitochondrial impairment in differentiated SK-N-SH cells.Endogenous RGS protein action modulates mu-opioid signaling through Galphao. Effects on adenylyl cyclase, extracellular signal-regulated kinases, and intracellular calcium pathways.Agonists activate Gi1 alpha or Gi2 alpha fused to the human mu opioid receptor differently.Analysis of agonist function at fusion proteins between the IP prostanoid receptor and cognate, unnatural and chimaeric G-proteins.A constitutively active mutant of the alpha 1B-adrenergic receptor can cause greater agonist-dependent down-regulation of the G-proteins G9 alpha and G11 alpha than the wild-type receptor.Stimulatory effects of opioids on transmitter release and possible cellular mechanisms: overview and original results.Analysis of inverse agonism at the delta opioid receptor after expression in Rat 1 fibroblasts.Dual bradykinin B2 receptor signalling in A431 human epidermoid carcinoma cells: activation of protein kinase C is counteracted by a GS-mediated stimulation of the cyclic AMP pathwayConstitutively active mutant GS alpha (G225T) and null-mutant G alpha i-2 (G203T) induce primitive endoderm from stem cells.Detection and analysis of agonist-induced formation of the complex of the stimulatory guanine nucleotide-binding protein with adenylate cyclase in intact wild-type and beta 2-adrenoceptor-expressing NG108-15 cells.Beta 3-adrenoceptor agonist-induced down-regulation of Gs alpha and functional desensitization in a Chinese hamster ovary cell line expressing a beta 3-adrenoceptor refractory to down-regulation.Alterations in the expression of G-proteins and regulation of adenylate cyclase in human neuroblastoma SH-SY5Y cells chronically exposed to low-efficacy mu-opioids.A novel N-terminal motif for palmitoylation of G-protein alpha subunits.Agonist activation of transfected human M1 muscarinic acetylcholine receptors in CHO cells results in down-regulation of both the receptor and the alpha subunit of the G-protein Gq.Immunoprecipitation of opioid receptor-Go-protein complexes using specific GTP-binding-protein antisera.Growth hormone decreases the response to anti-lipolytic agonists and decreases the levels of Gi2 in rat adipocytes.Gi3 does not contribute to the inhibition of adenylate cyclase when stimulation of an alpha 2-adrenergic receptor causes activation of both Gi2 and Gi3.Concurrent up-regulation of guanine-nucleotide-binding proteins Gi1 alpha, Gi2 alpha and Gi3 alpha in adipocytes of hypothyroid rats.
P2860
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P2860
Delta-opioid-receptor-mediated inhibition of adenylate cyclase is transduced specifically by the guanine-nucleotide-binding protein Gi2
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年学术文章
@wuu
1990年学术文章
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1990年学术文章
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1990年学术文章
@zh-my
1990年学术文章
@zh-sg
1990年學術文章
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1990年學術文章
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1990年學術文章
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name
Delta-opioid-receptor-mediated ...... nucleotide-binding protein Gi2
@en
type
label
Delta-opioid-receptor-mediated ...... nucleotide-binding protein Gi2
@en
prefLabel
Delta-opioid-receptor-mediated ...... nucleotide-binding protein Gi2
@en
P2860
P356
P1433
P1476
Delta-opioid-receptor-mediated ...... nucleotide-binding protein Gi2
@en
P2093
McKenzie FR
Milligan G
P2860
P304
P356
10.1042/BJ2670391
P407
P577
1990-04-01T00:00:00Z