The human delta opioid receptor activates G(i1)alpha more efficiently than G(o1)alpha.
about
Delta opioid activation of the mitogen-activated protein kinase cascade does not require transphosphorylation of receptor tyrosine kinasesDifferential modulation of mu-opioid receptor signaling to adenylyl cyclase by regulators of G protein signaling proteins 4 or 8 and 7 in permeabilised C6 cells is Galpha subtype dependent.Molecular basis of opioid dependence: role of signal regulation by G-proteins.Molecular Pharmacology of δ-Opioid Receptors.High- and low-affinity sites for sodium in δ-OR-Gi1α (Cys (351)-Ile (351)) fusion protein stably expressed in HEK293 cells; functional significance and correlation with biophysical state of plasma membrane.Co-expression of mu and delta opioid receptors as receptor-G protein fusions enhances both mu and delta signalling via distinct mechanisms.Endogenous RGS protein action modulates mu-opioid signaling through Galphao. Effects on adenylyl cyclase, extracellular signal-regulated kinases, and intracellular calcium pathways.Regulation of the avidity of ternary complexes containing the human 5-HT(1A) receptor by mutation of a receptor contact site on the interacting G protein alpha subunit.Agonists activate Gi1 alpha or Gi2 alpha fused to the human mu opioid receptor differently.Direct observation of G-protein binding to the human delta-opioid receptor using plasmon-waveguide resonance spectroscopy.Ligand-Directed Signaling at the Delta Opioid Receptor.
P2860
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P2860
The human delta opioid receptor activates G(i1)alpha more efficiently than G(o1)alpha.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
The human delta opioid receptor activates G(i1)alpha more efficiently than G(o1)alpha.
@en
type
label
The human delta opioid receptor activates G(i1)alpha more efficiently than G(o1)alpha.
@en
prefLabel
The human delta opioid receptor activates G(i1)alpha more efficiently than G(o1)alpha.
@en
P2093
P2860
P1476
The human delta opioid receptor activates G(i1)alpha more efficiently than G(o1)alpha
@en
P2093
P2860
P304
P356
10.1046/J.1471-4159.2001.00196.X
P407
P577
2001-03-01T00:00:00Z