Engineering the substrate specificity of Bacillus megaterium cytochrome P-450 BM3: hydroxylation of alkyl trimethylammonium compounds
about
Structural evidence: a single charged residue affects substrate binding in cytochrome P450 BM-3Evolutionary history of a specialized p450 propane monooxygenaseComparison of in vitro metabolism of ticlopidine by human cytochrome P450 2B6 and rabbit cytochrome P450 2B4Improving the activity of cytochrome P450 BM-3 catalyzing indole hydroxylation by directed evolution.High-specificity synthesis of novel monomers by remodeled alcohol hydroxylase.Combining substrate dynamics, binding statistics, and energy barriers to rationalize regioselective hydroxylation of octane and lauric acid by CYP102A1 and mutantsP450(BM3) (CYP102A1): connecting the dots.Roles of key active-site residues in flavocytochrome P450 BM3Detection of microwave radiation of cytochrome CYP102 A1 solution during the enzyme reaction.Insights into electron leakage in the reaction cycle of cytochrome P450 BM3 revealed by kinetic modeling and mutagenesis.Protein engineering of Bacillus megaterium CYP102. The oxidation of polycyclic aromatic hydrocarbons.Membrane binding and substrate access merge in cytochrome P450 7A1, a key enzyme in degradation of cholesterol.Kinetic analysis of hydroxylation of saturated fatty acids by recombinant P450foxy produced by an Escherichia coli expression system.Flavocytochrome P450 BM3 mutant A264E undergoes substrate-dependent formation of a novel heme iron ligand set.Semi-rational engineering of CYP153A35 to enhance ω-hydroxylation activity toward palmitic acid.Sequence-based screening for self-sufficient P450 monooxygenase from a metagenome library.Ionic liquid effects on the activity of monooxygenase P450 BM-3
P2860
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P2860
Engineering the substrate specificity of Bacillus megaterium cytochrome P-450 BM3: hydroxylation of alkyl trimethylammonium compounds
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Engineering the substrate spec ...... yl trimethylammonium compounds
@en
type
label
Engineering the substrate spec ...... yl trimethylammonium compounds
@en
prefLabel
Engineering the substrate spec ...... yl trimethylammonium compounds
@en
P2093
P2860
P356
P1433
P1476
Engineering the substrate spec ...... yl trimethylammonium compounds
@en
P2093
P2860
P304
P356
10.1042/BJ3270537
P407
P478
327 ( Pt 2)
P577
1997-10-01T00:00:00Z