Comparison of in vitro metabolism of ticlopidine by human cytochrome P450 2B6 and rabbit cytochrome P450 2B4 - Wikidata - awgldk - TriplyDB

Comparison of in vitro metabolism of ticlopidine by human cytochrome P450 2B6 and rabbit cytochrome P450 2B4

Comparison of in vitro metabolism of ticlopidine by human cytochrome P450 2B6 and rabbit cytochrome P450 2B4

http://www.wikidata.org/entity/Q34702595

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Differential oxidation of two thiophene-containing regioisomers to reactive metabolites by cytochrome P450 2C9 Detection and characterization of ticlopidine conjugates in rat bile using high-resolution mass spectrometry: applications of various data acquisition and processing tools.Mechanism-based inactivation of human cytochrome P450 2B6 by clopidogrel: involvement of both covalent modification of cysteinyl residue 475 and loss of heme Plasticity of CYP2B enzymes: structural and solution biophysical methods.Carbon-carbon bond cleavage and formation reactions in drug metabolism and the role of metabolic enzymes.Inhibitory Effects of Trapping Agents of Sulfur Drug Reactive Intermediates against Major Human Cytochrome P450 Isoforms.Structure and function of cytochromes P450 2B: from mechanism-based inactivators to X-ray crystal structures and back Halogen-π Interactions in the Cytochrome P450 Active Site: Structural Insights into Human CYP2B6 Substrate Selectivity.Use of phenoxyaniline analogs to generate biochemical insights into polybrominated diphenyl ether interaction with CYP2B enzymes.Quantitative in vitro phenotyping and prediction of drug interaction potential of CYP2B6 substrates as victims.Inhibition of angiotensin I converting enzyme by subtilisin NAT (nattokinase) in natto, a Japanese traditional fermented food.

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P2860

Comparison of in vitro metabolism of ticlopidine by human cytochrome P450 2B6 and rabbit cytochrome P450 2B4

http://www.wikidata.org/entity/Q34702595

description

2010 nî lūn-bûn

@nan

2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Comparison of in vitro metabol ...... and rabbit cytochrome P450 2B4

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Comparison of in vitro metabol ...... and rabbit cytochrome P450 2B4

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Comparison of in vitro metabol ...... and rabbit cytochrome P450 2B4

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Comparison of in vitro metabol ...... and rabbit cytochrome P450 2B4

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Comparison of in vitro metabol ...... and rabbit cytochrome P450 2B4

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Comparison of in vitro metabol ...... and rabbit cytochrome P450 2B4

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Comparison of in vitro metabol ...... and rabbit cytochrome P450 2B4

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Comparison of in vitro metabol ...... and rabbit cytochrome P450 2B4

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Comparison of in vitro metabol ...... and rabbit cytochrome P450 2B4

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Drug Metabolism and Disposition

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Comparison of in vitro metabol ...... and rabbit cytochrome P450 2B4

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Cathie Xiang

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Deepak Dalvie

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Gregory S Walker

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James R Halpert

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Jyothi C Talakad

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Manish B Shah

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P2860

Crystal structure of a cytochrome P450 2B6 genetic variant in complex with the inhibitor 4-(4-chlorophenyl)imidazole at 2.0-A resolution

Crystallographic studies on the complex behavior of nicotine binding to P450cam (CYP101)

Structural and Thermodynamic Consequences of 1-(4-Chlorophenyl)imidazole Binding to Cytochrome P450 2B4 † , ‡

Crystal Structures of Cytochrome P450 2B4 in Complex with the Inhibitor 1-Biphenyl-4-methyl-1 H -imidazole: Ligand-Induced Structural Response through α-Helical Repositioning ,

Structures of Cytochrome P450 2B4 Complexed with the Antiplatelet Drugs Ticlopidine and Clopidogrel,

The thienopyridine derivatives (platelet adenosine diphosphate receptor antagonists), pharmacology and clinical developments

In vitro inhibition of the cytochrome P450 (CYP450) system by the antiplatelet drug ticlopidine: potent effect on CYP2C19 and CYP2D6

THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. I. EVIDENCE FOR ITS HEMOPROTEIN NATURE

Structural features of cytochromes P450 and ligands that affect drug metabolism as revealed by X-ray crystallography and NMR.

Incidence and clinical course of thrombotic thrombocytopenic purpura due to ticlopidine following coronary stenting. EPISTENT Investigators. Evaluation of Platelet IIb/IIIa Inhibitor for Stenting.

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539-550

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10.1124/DMD.110.037101

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3

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39

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2010-12-14T00:00:00Z

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49682199

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21156812

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3061560

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