Two independent nuclear localization signals are present in the DNA-binding high-mobility group domains of SRY and SOX9.
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Phosphorylation of SOX9 by cyclic AMP-dependent protein kinase A enhances SOX9's ability to transactivate a Col2a1 chondrocyte-specific enhancerFunctional analysis of Sox10 mutations found in human Waardenburg-Hirschsprung patientsMenin, the product of the MEN1 gene, is a nuclear proteinThe high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factorsRAR agonists stimulate SOX9 gene expression in breast cancer cell lines: evidence for a role in retinoid-mediated growth inhibitionDirect interaction of SRY-related protein SOX9 and steroidogenic factor 1 regulates transcription of the human anti-Müllerian hormone geneDEDD, a novel death effector domain-containing protein, targeted to the nucleolusSox10 is an active nucleocytoplasmic shuttle protein, and shuttling is crucial for Sox10-mediated transactivationReview of the Y chromosome, Sry and hypertensionControl of cell fate and differentiation by Sry-related high-mobility-group box (Sox) transcription factorsDeterminants of DNA binding and bending by the Saccharomyces cerevisiae high mobility group protein NHP6A that are important for its biological activities. Role of the unique N terminus and putative intercalating methionine.Nuclear import of the yeast AP-1-like transcription factor Yap1p is mediated by transport receptor Pse1p, and this import step is not affected by oxidative stress.Differential regulation of transcription factors Stp1 and Stp2 in the Ssy1-Ptr3-Ssy5 amino acid sensing pathwayCompound effects of point mutations causing campomelic dysplasia/autosomal sex reversal upon SOX9 structure, nuclear transport, DNA binding, and transcriptional activationIdentification of functional domains in TdIF1 and its inhibitory mechanism for TdT activityA dominant-negative form of mouse SOX2 induces trophectoderm differentiation and progressive polyploidy in mouse embryonic stem cellsSox9 inhibits Wnt signaling by promoting beta-catenin phosphorylation in the nucleusMutations within Sox2/SOX2 are associated with abnormalities in the hypothalamo-pituitary-gonadal axis in mice and humansTranscriptional repression by the T-box proteins Tbx18 and Tbx15 depends on Groucho corepressorsSox2 induction by FGF and FGFR2 activating mutations inhibits Wnt signaling and osteoblast differentiationSOX7 transcription factor: sequence, chromosomal localisation, expression, transactivation and interference with Wnt signallingDetection of autoantibodies to the BTB-kelch protein KLHL7 in cancer sera.The metastasis suppressor SOX11 is an independent prognostic factor for improved survival in gastric cancer.A SRY-HMG box frame shift mutation inherited from a mosaic father with a mild form of testicular dysgenesis syndrome in Turner syndrome patientRegulation and expression of sexual differentiation factors in embryonic and extragonadal tissues of Atlantic salmon.Sex determination and the Y chromosome.Calpain 5 is highly expressed in the central nervous system (CNS), carries dual nuclear localization signals, and is associated with nuclear promyelocytic leukemia protein bodiesThe molecular mechanism for nuclear transport and its application.Two nuclear localization signals are required for nuclear translocation of nuclear factor 1-A.Calmodulin-dependent nuclear import of HMG-box family nuclear factors: importance of the role of SRY in sex reversal.A nuclear export signal within the high mobility group domain regulates the nucleocytoplasmic translocation of SOX9 during sexual determinationExportin 4 interacts with Sox9 through the HMG Box and inhibits the DNA binding of Sox9.The genetics of sex differences in brain and behavior.Regulation of male sexual development by Sry and Sox9.A novel MCPH1 isoform complements the defective chromosome condensation of human MCPH1-deficient cells.Structure-function relationships in human testis-determining factor SRY: an aromatic buttress underlies the specific DNA-bending surface of a high mobility group (HMG) box.Analysis of Sry duplications on the Rattus norvegicus Y-chromosomeDefective importin beta recognition and nuclear import of the sex-determining factor SRY are associated with XY sex-reversing mutations.Mechanisms of disease: Transcription factors in sex determination--relevance to human disorders of sex development.Calmodulin-driven nuclear entry: trigger for sex determination and terminal differentiation.
P2860
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P2860
Two independent nuclear localization signals are present in the DNA-binding high-mobility group domains of SRY and SOX9.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Two independent nuclear locali ...... group domains of SRY and SOX9.
@en
type
label
Two independent nuclear locali ...... group domains of SRY and SOX9.
@en
prefLabel
Two independent nuclear locali ...... group domains of SRY and SOX9.
@en
P2860
P356
P1476
Two independent nuclear locali ...... group domains of SRY and SOX9.
@en
P2093
P2860
P304
27848-27852
P356
10.1074/JBC.272.44.27848
P407
P577
1997-10-01T00:00:00Z