Runt homology domain proteins in osteoblast differentiation: AML3/CBFA1 is a major component of a bone-specific complex.
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Menin is required for bone morphogenetic protein 2- and transforming growth factor beta-regulated osteoblastic differentiation through interaction with Smads and Runx2Repression of Runx2 by androgen receptor (AR) in osteoblasts and prostate cancer cells: AR binds Runx2 and abrogates its recruitment to DNAGeneral transcription factor IIA-gamma increases osteoblast-specific osteocalcin gene expression via activating transcription factor 4 and runt-related transcription factor 2Modulation of Runx2 activity by estrogen receptor-alpha: implications for osteoporosis and breast cancerCritical role of activating transcription factor 4 in the anabolic actions of parathyroid hormone in boneRunx2- and histone deacetylase 3-mediated repression is relieved in differentiating human osteoblast cells to allow high bone sialoprotein expressionMaturational disturbance of chondrocytes in Cbfa1-deficient miceNkx3.2-mediated repression of Runx2 promotes chondrogenic differentiationMice Deficient in AKAP13 (BRX) Are Osteoporotic and Have Impaired OsteogenesisBone-specific transcription factor Runx2 interacts with the 1alpha,25-dihydroxyvitamin D3 receptor to up-regulate rat osteocalcin gene expression in osteoblastic cellsThe protein kinase C pathway plays a central role in the fibroblast growth factor-stimulated expression and transactivation activity of Runx2Interaction of the 1alpha,25-dihydroxyvitamin D3 receptor at the distal promoter region of the bone-specific osteocalcin gene requires nucleosomal remodellingRegulation of the bone-specific osteocalcin gene by p300 requires Runx2/Cbfa1 and the vitamin D3 receptor but not p300 intrinsic histone acetyltransferase activityADAR1 ablation decreases bone mass by impairing osteoblast function in miceFoxo1 mediates insulin-like growth factor 1 (IGF1)/insulin regulation of osteocalcin expression by antagonizing Runx2 in osteoblastsTranscriptional coactivation of bone-specific transcription factor Cbfa1 by TAZProliferation and osteogenic differentiation of mesenchymal stem cells induced by a short isoform of NELL-1Human umbilical cord blood-derived CD34+ cells reverse osteoporosis in NOD/SCID mice by altering osteoblastic and osteoclastic activitiesNon-virus-mediated transfer of siRNAs against Runx2 and Smad4 inhibit heterotopic ossification in rats.The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasionExpression screening of factors binding to the osteocalcin bone-specific promoter element OC box I: isolation of a novel osteoblast differentiation-specific factor.Retinoblastoma binding protein-1 (RBP1) is a Runx2 coactivator and promotes osteoblastic differentiation.Reciprocal control of osteoblast/chondroblast and osteoblast/adipocyte differentiation of multipotential clonal human marrow stromal F/STRO-1(+) cells.ChIP Display: novel method for identification of genomic targets of transcription factors.A positive role of microRNA-15b on regulation of osteoblast differentiation.The gene for aromatase, a rate-limiting enzyme for local estrogen biosynthesis, is a downstream target gene of Runx2 in skeletal tissues.Bone metastatic LNCaP-derivative C4-2B prostate cancer cell line mineralizes in vitro.The bone-specific expression of Runx2 oscillates during the cell cycle to support a G1-related antiproliferative function in osteoblasts.Multiple Cbfa/AML sites in the rat osteocalcin promoter are required for basal and vitamin D-responsive transcription and contribute to chromatin organization.Runx2 is a common target of transforming growth factor beta1 and bone morphogenetic protein 2, and cooperation between Runx2 and Smad5 induces osteoblast-specific gene expression in the pluripotent mesenchymal precursor cell line C2C12.runt homology domain transcription factors (Runx, Cbfa, and AML) mediate repression of the bone sialoprotein promoter: evidence for promoter context-dependent activity of Cbfa proteins.Links among growth factors, hormones, and nuclear factors with essential roles in bone formation.Calcium-mediated stress kinase activation by DMP1 promotes osteoblast differentiation.BMP2-activated Erk/MAP kinase stabilizes Runx2 by increasing p300 levels and histone acetyltransferase activityOptimisation of the differing conditions required for bone formation in vitro by primary osteoblasts from mice and rats.Generation of rodent and human osteoblasts.Effect of nanofiber content on bone regeneration of silk fibroin/poly(ε-caprolactone) nano/microfibrous composite scaffolds.1alpha,25-dihydroxy vitamin D(3) induces nuclear matrix association of the 1alpha,25-dihydroxy vitamin D(3) receptor in osteoblasts independently of its ability to bind DNAIntranuclear trafficking of transcription factors: Requirements for vitamin D-mediated biological control of gene expression.The cleidocranial dysplasia-related R131G mutation in the Runt-related transcription factor RUNX2 disrupts binding to DNA but not CBF-beta.
P2860
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P2860
Runt homology domain proteins in osteoblast differentiation: AML3/CBFA1 is a major component of a bone-specific complex.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Runt homology domain proteins ...... nt of a bone-specific complex.
@en
type
label
Runt homology domain proteins ...... nt of a bone-specific complex.
@en
prefLabel
Runt homology domain proteins ...... nt of a bone-specific complex.
@en
P2093
P2860
P1476
Runt homology domain proteins ...... nt of a bone-specific complex.
@en
P2093
Banerjee C
Hiebert SW
P2860
P356
10.1002/(SICI)1097-4644(19970701)66:1<1::AID-JCB1>3.0.CO;2-V
P577
1997-07-01T00:00:00Z