Kinetic mechanism whereby DNA polymerase I (Klenow) replicates DNA with high fidelity.
about
Measuring cation dependent DNA polymerase fidelity landscapes by deep sequencingE. coli DNA polymerase I as a reverse transcriptaseFidelity of DNA synthesis catalyzed by human DNA polymerase alpha and HIV-1 reverse transcriptase: effect of reaction pHDNA-templated polymerization of side-chain-functionalized peptide nucleic acid aldehydesSurface plasmon field-enhanced fluorescence spectroscopy studies of primer extension reactions.Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations.Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystalDNA replication error-induced extinction of diploid yeastCrystal structures of a ddATP-, ddTTP-, ddCTP, and ddGTP- trapped ternary complex of Klentaq1: insights into nucleotide incorporation and selectivityCrystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: structural basis for nucleotide incorporation.DNA polymerase fidelity: comparing direct competition of right and wrong dNTP substrates with steady state and pre-steady state kineticsHuman DNA repair systems: an overview.Normally lethal amino acid substitutions suppress an ultramutator DNA Polymerase δ variantVariations on a theme: eukaryotic Y-family DNA polymerasesCharacterization of background noise in capture-based targeted sequencing data.Antimutator mutations in the alpha subunit of Escherichia coli DNA polymerase III: identification of the responsible mutations and alignment with other DNA polymerasesTemplating efficiency of naked DNA.Difluorotoluene, a Nonpolar Isostere for Thymine, Codes Specifically and Efficiently for Adenine in DNA Replication.Minor Groove Interactions between Polymerase and DNA: More Essential to Replication than Watson-Crick Hydrogen Bonds?Pre-steady state kinetic studies of the fidelity of nucleotide incorporation by yeast DNA polymerase deltaVaried Molecular Interactions at the Active Sites of Several DNA Polymerases: Nonpolar Nucleoside Isosteres as Probes.Highly organized but pliant active site of DNA polymerase beta: compensatory mechanisms in mutant enzymes revealed by dynamics simulations and energy analyses.In silico studies of the African swine fever virus DNA polymerase X support an induced-fit mechanismThe thermodynamics of template-directed DNA synthesis: base insertion and extension enthalpies.Kinetic approaches to understanding the mechanisms of fidelity of the herpes simplex virus type 1 DNA polymeraseDirect electrical detection of DNA synthesis.DNA polymerase fidelity: from genetics toward a biochemical understanding.Significant contribution of the 3'→5' exonuclease activity to the high fidelity of nucleotide incorporation catalyzed by human DNA polymerase ϵ.Comparative study of mutagenesis by O6-methylguanine in the human Ha-ras oncogene in E. coli and in vitroInhibitors of HIV-1 reverse transcriptase and fidelity of in vitro DNA replication.Effects of Escherichia coli dnaE antimutator alleles in a proofreading-deficient mutD5 strain.dNTP pool levels modulate mutator phenotypes of error-prone DNA polymerase ε variants.Human DNA Polymerase ν Catalyzes Correct and Incorrect DNA Synthesis with High Catalytic Efficiency.Enzymatic activities of overexpressed herpes simplex virus DNA polymerase purified from recombinant baculovirus-infected insect cells.Proofreading DNA: recognition of aberrant DNA termini by the Klenow fragment of DNA polymerase IThe 3'-5' exonuclease of DNA polymerase I of Escherichia coli: contribution of each amino acid at the active site to the reaction.Extension of base mispairs by Taq DNA polymerase: implications for single nucleotide discrimination in PCR.Hydrogen bonding revisited: geometric selection as a principal determinant of DNA replication fidelity.Conformational changes induced in herpes simplex virus DNA polymerase upon DNA binding.An Escherichia coli dnaE mutation with suppressor activity toward mutator mutD5
P2860
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P2860
Kinetic mechanism whereby DNA polymerase I (Klenow) replicates DNA with high fidelity.
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
1988年论文
@zh
1988年论文
@zh-cn
name
Kinetic mechanism whereby DNA polymerase I (Klenow) replicates DNA with high fidelity.
@en
type
label
Kinetic mechanism whereby DNA polymerase I (Klenow) replicates DNA with high fidelity.
@en
prefLabel
Kinetic mechanism whereby DNA polymerase I (Klenow) replicates DNA with high fidelity.
@en
P2093
P356
P1433
P1476
Kinetic mechanism whereby DNA polymerase I (Klenow) replicates DNA with high fidelity.
@en
P2093
Benkovic P
Benkovic SJ
P304
P356
10.1021/BI00418A012
P407
P577
1988-09-01T00:00:00Z