Herpes simplex virus regulatory elements and the immunoglobulin octamer domain bind a common factor and are both targets for virion transactivation.
about
Potential role for luman, the cellular homologue of herpes simplex virus VP16 (alpha gene trans-inducing factor), in herpesvirus latencyThe novel coactivator C1 (HCF) coordinates multiprotein enhancer formation and mediates transcription activation by GABPZhangfei: a second cellular protein interacts with herpes simplex virus accessory factor HCF in a manner similar to Luman and VP16.The cellular C1 factor of the herpes simplex virus enhancer complex is a family of polypeptidesLuman, a new member of the CREB/ATF family, binds to herpes simplex virus VP16-associated host cellular factorAssociation of a protein phosphatase 1 activity with the human factor C1 (HCF) complexThe herpesvirus transactivator VP16 mimics a human basic domain leucine zipper protein, luman, in its interaction with HCFThe octamer-binding proteins Oct-1 and Oct-2 repress the HIV long terminal repeat promoter and its transactivation by TatA single serine residue at position 375 of VP16 is critical for complex assembly with Oct-1 and HCF and is a target of phosphorylation by casein kinase IIHCF-dependent nuclear import of VP16A novel 50-kilodalton fragment of host cell factor 1 (C1) in G(0) cellsOct-6: a POU transcription factor expressed in embryonal stem cells and in the developing brainPattern of aromatic and hydrophobic amino acids critical for one of two subdomains of the VP16 transcriptional activatorPositive and negative elements regulate a melanocyte-specific promoterInteraction of HCF-1 with a cellular nuclear export factorInteraction of Oct-1 and automodification domain of poly(ADP-ribose) synthetaseNuclear localization of the C1 factor (host cell factor) in sensory neurons correlates with reactivation of herpes simplex virus from latencyThe mouse homologue of the human transcription factor C1 (host cell factor). Conservation of forms and functionThe ability of POU family transcription factors to activate or repress gene expression is dependent on the spacing and context of their specific response elementsInteraction between a novel F9-specific factor and octamer-binding proteins is required for cell-type-restricted activity of the fibroblast growth factor 4 enhancerOct-1 and Oct-2 potentiate functional interactions of a transcription factor with the proximal sequence element of small nuclear RNA genesThe Oct-2 transcription factor represses tyrosine hydroxylase expression via a heptamer TAATGARAT-like motif in the gene promoterStructural analysis and transcriptional mapping of the Marek's disease virus gene encoding pp38, an antigen associated with transformed cells.Phylogenetic footprinting reveals a nuclear protein which binds to silencer sequences in the human gamma and epsilon globin genesThe major tegument structural protein VP22 targets areas of dispersed nucleolin and marginalized chromatin during productive herpes simplex virus 1 infection.Nuclear proteins that bind the human gamma-globin gene promoter: alterations in binding produced by point mutations associated with hereditary persistence of fetal hemoglobin.Octamer transcription factors bind to two different sequence motifs of the immunoglobulin heavy chain promoterFunctionality of the GAL4/UAS system in Tribolium requires the use of endogenous core promotersThe octamer-binding proteins form multi-protein--DNA complexes with the HSV alpha TIF regulatory proteinA herpesvirus trans-activating protein interacts with transcription factor OTF-1 and other cellular proteinsTowards an understanding of the herpes simplex virus type 1 latency-reactivation cycleMutational analysis of the promoter region of the alpha 27 gene of herpes simplex virus 1 within the context of the viral genome.HSV-1 ICP27 represses NF-κB activity by regulating Daxx sumoylationTargeting the microphthalmia basic helix-loop-helix-leucine zipper transcription factor to a subset of E-box elements in vitro and in vivoAnalysis of HCF, the cellular cofactor of VP16, in herpes simplex virus-infected cells.Transactivation of herpes simplex virus type 1 immediate-early gene expression by virion-associated factors is blocked by an inhibitor of cyclin-dependent protein kinasesAnalysis of homeodomain function by structure-based design of a transcription factor.Transcriptional activation of the human hematopoietic prostaglandin D synthase gene in megakaryoblastic cells. Roles of the oct-1 element in the 5'-flanking region and the AP-2 element in the untranslated exon 1.The acidic transcriptional activator GAL-VP16 acts on preformed template-committed complexes.HSV-1-based vectors for gene therapy of neurological diseases and brain tumors: part I. HSV-1 structure, replication and pathogenesis.
P2860
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P2860
Herpes simplex virus regulatory elements and the immunoglobulin octamer domain bind a common factor and are both targets for virion transactivation.
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
1988年论文
@zh
1988年论文
@zh-cn
name
Herpes simplex virus regulator ...... ts for virion transactivation.
@en
type
label
Herpes simplex virus regulator ...... ts for virion transactivation.
@en
prefLabel
Herpes simplex virus regulator ...... ts for virion transactivation.
@en
P1433
P1476
Herpes simplex virus regulator ...... ts for virion transactivation.
@en
P2093
P304
P356
10.1016/S0092-8674(88)80036-9
P407
P577
1988-02-01T00:00:00Z