Bile acids up-regulate death receptor 5/TRAIL-receptor 2 expression via a c-Jun N-terminal kinase-dependent pathway involving Sp1.
about
Genome sequence of Anopheles sinensis provides insight into genetics basis of mosquito competence for malaria parasitesAmeliorated ConA-induced hepatitis in the absence of PKC-thetaHIV induces TRAIL sensitivity in hepatocytesInhibition of ataxia telangiectasia mutated kinase activity enhances TRAIL-mediated apoptosis in human melanoma cellsTranscriptional regulation of bone morphogenetic protein 4 by tumor necrosis factor and its relationship with age-related macular degeneration.Transcription factor NF-kappaB differentially regulates death receptor 5 expression involving histone deacetylase 1.Poly(ADP-ribose) polymerase inhibitors sensitize cancer cells to death receptor-mediated apoptosis by enhancing death receptor expression.Cyclic AMP-guanine exchange factor activation inhibits JNK-dependent lipopolysaccharide-induced apoptosis in rat hepatocytes.TRAIL dependent fratricidal killing of gp120 primed hepatocytes by HCV core expressing hepatocytes.Biliary apotopes and anti-mitochondrial antibodies activate innate immune responses in primary biliary cirrhosisHepatocyte death: a clear and present danger.Regulation of the extrinsic apoptotic pathway by microRNA-21 in alcoholic liver injuryBile acids and cytokines inhibit the human cholesterol 7 alpha-hydroxylase gene via the JNK/c-jun pathway in human liver cellsSequential treatment by ionizing radiation and sodium arsenite dramatically accelerates TRAIL-mediated apoptosis of human melanoma cells.Epigenetics--an epicenter of gene regulation: histones and histone-modifying enzymes.Molecular mechanisms of ursodeoxycholic acid toxicity & side effects: ursodeoxycholic acid freezes regeneration & induces hibernation mode.PP2A inhibitors arrest G2/M transition through JNK/Sp1- dependent down-regulation of CDK1 and autophagy-dependent up-regulation of p21.Inhibition of NF-κB by deoxycholic acid induces miR-21/PDCD4-dependent hepatocelular apoptosis.Phosphorylation by c-Jun NH2-terminal kinase 1 regulates the stability of transcription factor Sp1 during mitosisStructure-dependent activation of endoplasmic reticulum stress-mediated apoptosis in pancreatic cancer by 1,1-bis(3'-indoly)-1-(p-substituted phenyl)methanes.IGF-1R contributes to stress-induced hepatocellular damage in experimental cholestasis.Hepatocyte-specific NEMO deletion promotes NK/NKT cell- and TRAIL-dependent liver damage.Hepatic 3D spheroid models for the detection and study of compounds with cholestatic liability.Apoptosis and necrosis in the liverImmune-mediated liver diseases: programmed cell death ligands and circulating apoptotic markers.c-Jun N-terminal kinase 1/c-Jun activation of the p53/microRNA 34a/sirtuin 1 pathway contributes to apoptosis induced by deoxycholic acid in rat liver.Bile acid receptors as targets for drug development.Infliximab as a treatment option for patients with rheumatoid arthritis and primary biliary cirrhosis.Inhibition of JNK signalling mediates PPARα-dependent protection against intrahepatic cholestasis by fenofibrate.Inhibition of Notch1 signaling overcomes resistance to the death ligand Trail by specificity protein 1-dependent upregulation of death receptor 5.Intracellular localization of DR5 and related regulatory pathways as a mechanism of resistance to TRAIL in cancer.Sodium taurocholate cotransporting polypeptide mediates dual actions of deoxycholic acid in human hepatocellular carcinoma cells: enhanced apoptosis versus growth stimulation.Inhibition of Yin Yang 1-dependent repressor activity of DR5 transcription and expression by the novel proteasome inhibitor NPI-0052 contributes to its TRAIL-enhanced apoptosis in cancer cells.Inhibitory effects of Ligusticum chuanxiong on the proliferation of rat hepatic stellate cells.Bile salt-induced pro-oxidant liver damage promotes transplanted cell proliferation for correcting Wilson disease in the Long-Evans Cinnamon rat model.Autoactivation of the Epstein-Barr virus oncogenic protein LMP1 during type II latency through opposite roles of the NF-kappaB and JNK signaling pathways.Free fatty acids sensitise hepatocytes to TRAIL mediated cytotoxicityImpaired bile acid handling and aggravated liver injury in mice expressing a hepatocyte-specific RXRα variant lacking the DNA-binding domain.Tumour necrosis factor related apoptosis inducing ligand (TRAIL) induces hepatic steatosis in viral hepatitis and after alcohol intake.Valproic acid sensitizes TRAIL-resistant anaplastic thyroid carcinoma cells to apoptotic cell death.
P2860
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P2860
Bile acids up-regulate death receptor 5/TRAIL-receptor 2 expression via a c-Jun N-terminal kinase-dependent pathway involving Sp1.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Bile acids up-regulate death r ...... pendent pathway involving Sp1.
@en
type
label
Bile acids up-regulate death r ...... pendent pathway involving Sp1.
@en
prefLabel
Bile acids up-regulate death r ...... pendent pathway involving Sp1.
@en
P2093
P356
P1476
Bile acids up-regulate death r ...... ependent pathway involving Sp1
@en
P2093
Annette Grambihler
Hajime Higuchi
Steven F Bronk
P356
10.1074/JBC.M309476200
P407
P577
2003-10-14T00:00:00Z