Reduced folate carrier gene silencing in multiple antifolate-resistant tumor cell lines is due to a simultaneous loss of function of multiple transcription factors but not promoter methylation.
about
Folate deprivation results in the loss of breast cancer resistance protein (BCRP/ABCG2) expression. A role for BCRP in cellular folate homeostasis.Methotrexate resistance in relation to treatment outcome in childhood acute lymphoblastic leukemia.Pharmacogenetics of methotrexate.Epigenetic alterations in folate transport genes in placental tissue from fetuses with neural tube defects and in leukocytes from subjects with hyperhomocysteinemiaAn update on methotrexate pharmacogenetics in rheumatoid arthritis.Decitabine impact on the endocytosis regulator RhoA, the folate carriers RFC1 and FOLR1, and the glucose transporter GLUT4 in human tumors.The major facilitative folate transporters solute carrier 19A1 and solute carrier 46A1: biology and role in antifolate chemotherapy of cancer.Current concepts in the genetic diagnostics of rheumatoid arthritis.Aberrant methylation in the promoter region of the reduced folate carrier gene is a potential mechanism of resistance to methotrexate in primary central nervous system lymphomas.
P2860
Q33200355-5C733845-0DA0-458B-A209-A751099F21A0Q35684384-C993B66B-8D95-4A36-A338-369C032231A9Q35911142-70F1DBF9-0C9C-47FB-9410-3E063EFAE135Q36891923-C8CF1A27-9746-439D-9184-BD0BDD7CCD5DQ37126658-5AB1CEFA-5EA5-418C-B204-908A347B199CQ37493954-A571CE47-8404-42D3-9F9A-6D0E6EE36026Q37663377-CDA3F978-3E3C-4B72-87F4-ACCEA19AA706Q42970803-611BC287-9EDA-4C6E-B16B-2CA07261AEB1Q45028998-5C62348B-8E52-4D5A-BD19-54525F8484E2
P2860
Reduced folate carrier gene silencing in multiple antifolate-resistant tumor cell lines is due to a simultaneous loss of function of multiple transcription factors but not promoter methylation.
description
2003 nî lūn-bûn
@nan
2003年の論文
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2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
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2003年论文
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2003年论文
@zh-cn
name
Reduced folate carrier gene si ...... but not promoter methylation.
@en
type
label
Reduced folate carrier gene si ...... but not promoter methylation.
@en
prefLabel
Reduced folate carrier gene si ...... but not promoter methylation.
@en
P2860
P50
P356
P1476
Reduced folate carrier gene si ...... s but not promoter methylation
@en
P2093
Lilah Rothem
Yotam Kaufman
P2860
P304
P356
10.1074/JBC.M309092200
P407
P577
2003-10-09T00:00:00Z