Biosynthesis, processing, and targeting of sphingolipid activator protein (SAP )precursor in cultured human fibroblasts. Mannose 6-phosphate receptor-independent endocytosis of SAP precursor.
about
Transport of human lysosomal neuraminidase to mature lysosomes requires protective protein/cathepsin A.The protective role of prosaposin and its receptors in the nervous systemAggresomes: a cellular response to misfolded proteinsNeurological deficits and glycosphingolipid accumulation in saposin B deficient mice.Identification of a novel sequence involved in lysosomal sorting of the sphingolipid activator protein prosaposin.Crystallization and preliminary characterization of three different crystal forms of human saposin C heterologously expressed in Pichia pastoris.Purified recombinant human prosaposin forms oligomers that bind procathepsin D and affect its autoactivation.Impaired prosaposin lysosomal trafficking in frontotemporal lobar degeneration due to progranulin mutationsCellular uptake of saposin (SAP) precursor and lysosomal delivery by the low density lipoprotein receptor-related protein (LRP).The exogenous pathway for antigen presentation on major histocompatibility complex class II and CD1 molecules.Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin.Regional expression of prosaposin in the wild-type and saposin D-deficient mouse brain detected by an anti-mouse prosaposin-specific antibody.Endosomal processing for antigen presentation mediated by CD1 and Class I major histocompatibility complex: roads to display or destruction.Sphingolipids: the nexus between Gaucher disease and insulin resistance.Proteinases and their inhibitors in liver cancer.My journey into the world of sphingolipids and sphingolipidoses.Saposin C is required for normal resistance of acid beta-glucosidase to proteolytic degradation.Lrp1/LDL Receptor Play Critical Roles in Mannose 6-Phosphate-Independent Lysosomal Enzyme Targeting.Quantitative Analysis of the Proteome Response to the Histone Deacetylase Inhibitor (HDACi) Vorinostat in Niemann-Pick Type C1 disease.The lipoprotein receptor-related protein-1 (LRP) adapter protein GULP mediates trafficking of the LRP ligand prosaposin, leading to sphingolipid and free cholesterol accumulation in late endosomes and impaired efflux.Gaucher disease mouse models: point mutations at the acid beta-glucosidase locus combined with low-level prosaposin expression lead to disease variants.Saposin C is required for lipid presentation by human CD1bStructural and membrane-binding properties of saposin D
P2860
Q24533181-BEE76FF3-75B3-40EC-A6A4-0BF7B5740ABFQ27014092-6657BE70-5342-493A-812B-72AE09379272Q28292275-38DBA934-167B-4F86-AA17-9E798C8D989AQ28594479-4D3A06DA-D4F8-4CF6-821C-F0C4E5496204Q30872172-CD07F571-D35A-4E8B-8A37-5C5033D40D38Q31033356-7E7824EC-F7DA-4127-9C88-93E4084BA8CDQ33204778-29FE84C7-8A7F-4458-9B91-2616F26765ECQ33815765-C548B3BC-922A-4A69-B8B3-AA8E5F45577EQ33889265-5399C435-976B-46DF-8846-F099D220DC62Q35821240-2110FB37-7AE3-419F-8858-564FAACBF844Q36078240-770DB121-C728-4DB7-904A-AEB7171D6E68Q36753118-2E78261F-13F3-4722-BDA2-18E698A32C13Q37498956-6B0347E6-F89F-4DE1-ADE2-E768E036B913Q37799400-0B10231B-5C01-4E98-B5BE-1E4674714A4CQ37821301-FB93B653-C3D1-4F0C-9C35-415FFD799AA9Q38066410-E569CAE8-5B6D-402F-A115-3BAAF6FED705Q44482194-15068C56-56E4-478E-8E61-5FE140C294C7Q45874055-FBACD88A-A326-4B7D-BC6B-CF877305E678Q46094394-FFD606AA-CFFD-423C-B62F-6C0F8BF202BFQ46960355-587927A6-A0D6-4004-80BB-5F13CDD5841DQ53663619-D7394AF4-D72D-45B6-AFF7-B37DA36951E2Q57081058-80DC0245-BAD4-4738-9E7D-DA0DC81CD770Q57631498-A2299BCE-F234-45FE-8355-819EE7DCD681
P2860
Biosynthesis, processing, and targeting of sphingolipid activator protein (SAP )precursor in cultured human fibroblasts. Mannose 6-phosphate receptor-independent endocytosis of SAP precursor.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Biosynthesis, processing, and ...... endocytosis of SAP precursor.
@en
type
label
Biosynthesis, processing, and ...... endocytosis of SAP precursor.
@en
prefLabel
Biosynthesis, processing, and ...... endocytosis of SAP precursor.
@en
P2093
P2860
P356
P1476
Biosynthesis, processing, and ...... endocytosis of SAP precursor.
@en
P2093
Sandhoff K
Vielhaber G
P2860
P304
32438-32446
P356
10.1074/JBC.271.50.32438
P407
P577
1996-12-01T00:00:00Z