Stat3 recruitment by two distinct ligand-induced, tyrosine-phosphorylated docking sites in the interleukin-10 receptor intracellular domain.
about
Etk, a Btk family tyrosine kinase, mediates cellular transformation by linking Src to STAT3 activation.ErbB-2 activates Stat3 alpha in a Src- and JAK2-dependent mannerRole of the interleukin (IL)-28 receptor tyrosine residues for antiviral and antiproliferative activity of IL-29/interferon-lambda 1: similarities with type I interferon signalingStructural requirements for signal transducer and activator of transcription 3 binding to phosphotyrosine ligands containing the YXXQ motifThe orphan receptor CRF2-4 is an essential subunit of the interleukin 10 receptorIdentification and functional characterization of a second chain of the interleukin-10 receptor complex.Kinetics of regulated protein-protein interactions revealed with firefly luciferase complementation imaging in cells and living animalsRegulation of IL-10 and IL-12 production and function in macrophages and dendritic cellsRegulation of interleukin-10 receptor ubiquitination and stability by beta-TrCP-containing ubiquitin E3 ligasePhosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformationcDNA cloning, genomic structure, molecular characterization and mRNA expression analysis of the Pekin duck interleukin-10 receptor 1.Characterization of phosphopeptide motifs specific for the Src homology 2 domains of signal transducer and activator of transcription 1 (STAT1) and STAT3.Interleukin-10 and Gp130 cytokines in human multiple myeloma.Non-cell-autonomous activation of IL-6/STAT3 signaling mediates FGF19-driven hepatocarcinogenesis.A single amino acid substitution in the v-Eyk intracellular domain results in activation of Stat3 and enhances cellular transformation.IL-10 inhibits macrophage activation and proliferation by distinct signaling mechanisms: evidence for Stat3-dependent and -independent pathwaysIL-10 induces a STAT3-dependent autoregulatory loop in TH2 cells that promotes Blimp-1 restriction of cell expansion via antagonism of STAT5 target genesJak-Stat signal transduction pathway through the eyes of cytokine class II receptor complexes.Roles of STAT3 defined by tissue-specific gene targeting.Down-regulation of interleukin-8 secretion from Mycobacterium tuberculosis-infected monocytes by interleukin-4 and -10 but not by interleukin-13.Role of interleukin 10 transcriptional regulation in inflammation and autoimmune diseaseAn emerging role for the anti-inflammatory cytokine interleukin-10 in dengue virus infection.IL-10/Janus kinase/signal transducer and activator of transcription 3 signaling dysregulates Bim expression in autoimmune lymphoproliferative syndromeThe intracellular domain of interferon-alpha receptor 2c (IFN-alphaR2c) chain is responsible for Stat activation.Inhibition of interleukin 10 signaling after Fc receptor ligation and during rheumatoid arthritisA single amino acid determines the immunostimulatory activity of interleukin 10.Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice.Interleukin 10 receptor signaling: master regulator of intestinal mucosal homeostasis in mice and humans.Human leukocyte antigen-G expression in differentiated human airway epithelial cells: lack of modulation by Th2-associated cytokines.Differential T Cell Cytokine Receptivity and Not Signal Quality Distinguishes IL-6 and IL-10 Signaling during Th17 DifferentiationThe straw that stirs the drink: insight into the pathogenesis of inflammatory bowel disease revealed through the study of microflora-induced inflammation in genetically modified mice.Infection-induced IL-10 and JAK-STAT: A review of the molecular circuitry controlling immune hyperactivity in response to pathogenic microbes.Molecular approaches towards the inhibition of the signal transducer and activator of transcription 3 (Stat3) protein.Regulation of interferon and Toll-like receptor signaling during macrophage activation by opposing feedforward and feedback inhibition mechanisms.Inflammatory bowel disease and mutations affecting the interleukin-10 receptor.The therapeutic potential of interleukin-10 in neuroimmune diseases.Reprogramming macrophage orientation by microRNA 146b targeting transcription factor IRF5Signal transducer and activator of transcription 3 inhibitors: a patent review.Role of interleukin-10 and interleukin-10 receptor in systemic lupus erythematosus.STAT heterodimers in immunity: A mixed message or a unique signal?
P2860
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P2860
Stat3 recruitment by two distinct ligand-induced, tyrosine-phosphorylated docking sites in the interleukin-10 receptor intracellular domain.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Stat3 recruitment by two disti ...... receptor intracellular domain.
@en
type
label
Stat3 recruitment by two disti ...... receptor intracellular domain.
@en
prefLabel
Stat3 recruitment by two disti ...... receptor intracellular domain.
@en
P2093
P2860
P356
P1476
Stat3 recruitment by two disti ...... receptor intracellular domain.
@en
P2093
Darnell JE
Greenlund AC
Schreiber RD
Weber-Nordt RM
P2860
P304
27954-27961
P356
10.1074/JBC.271.44.27954
P407
P577
1996-11-01T00:00:00Z