Functional analysis of the cytoplasmic domain of the human Mpl receptor for tyrosine-phosphorylation of the signaling molecules, proliferation and differentiation.
about
Regulatory and signaling properties of the Vav familyMultiple roles of Rap1 in hematopoietic cells: complementary versus antagonistic functionsThrombopoietin signal transduction requires functional JAK2, not TYK2Thrombopoietin.Autoantibody to c-Mpl (thrombopoietin receptor) in systemic lupus erythematosus: relationship to thrombocytopenia with megakaryocytic hypoplasia.The Thrombopoietin Receptor: Structural Basis of Traffic and Activation by Ligand, Mutations, Agonists, and Mutated Calreticulin.Plasma thrombopoietin (TPO) levels and expression of TPO receptor on platelets in patients with myelodysplastic syndromes.Involvement of prolonged ras activation in thrombopoietin-induced megakaryocytic differentiation of a human factor-dependent hematopoietic cell lineThrombopoietin-mediated sustained activation of extracellular signal-regulated kinase in UT7-Mpl cells requires both Ras-Raf-1- and Rap1-B-Raf-dependent pathwaysEnu mutagenesis identifies a novel platelet phenotype in a loss-of-function Jak2 allele.Thrombin cleaves recombinant human thrombopoietin: one of the proteolytic events that generates truncated forms of thrombopoietinControl of thrombopoietin-induced megakaryocytic differentiation by the mitogen-activated protein kinase pathway.Design of conditionally active STATs: insights into STAT activation and gene regulatory function.Role of the distal half of the c-Mpl intracellular domain in control of platelet production by thrombopoietin in vivo.Janus kinases affect thrombopoietin receptor cell surface localization and stability.Dissection of the cytoplasmic domains of cytokine receptors involved in STAT and Ras dependent proliferation.Studies with chimeric Mpl/JAK2 receptors indicate that both JAK2 and the membrane-proximal domain of Mpl are required for cellular proliferation.Thrombopoietin-induced conformational change in p53 lies downstream of the p44/p42 mitogen activated protein kinase cascade in the human growth factor-dependent cell line M07e.Thrombopoietin stimulates proliferation and megakaryocytic differentiation of mouse pro-B cell line BF-TE22A new feature of Mpl receptor: ligand-induced transforming activity in FRE rat fibroblasts.Peptide immobilized on gold particles enhances cell growth.Thrombopoietin level is inversely related to blast count, not platelet number, in Down syndrome neonates with transient myeloproliferative disorder.Quantitative analysis of thrombopoietin receptors on human megakaryocytes.
P2860
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P2860
Functional analysis of the cytoplasmic domain of the human Mpl receptor for tyrosine-phosphorylation of the signaling molecules, proliferation and differentiation.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Functional analysis of the cyt ...... iferation and differentiation.
@en
type
label
Functional analysis of the cyt ...... iferation and differentiation.
@en
prefLabel
Functional analysis of the cyt ...... iferation and differentiation.
@en
P2093
P2860
P1433
P1476
Functional analysis of the cyt ...... iferation and differentiation.
@en
P2093
P2860
P304
P356
10.1016/0014-5793(96)01047-2
P407
P577
1996-10-01T00:00:00Z