Site-specific synthesis and reactivity of oligonucleotides containing stereochemically defined 1,N2-deoxyguanosine adducts of the lipid peroxidation product trans-4-hydroxynonenal.
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4-Hydroxy-nonenal-A Bioactive Lipid Peroxidation ProductPathways for repairing and tolerating the spectrum of oxidative DNA lesionsThe Stereochemistry of trans -4-Hydroxynonenal-Derived Exocyclic 1, N 2 -2′-Deoxyguanosine Adducts Modulates Formation of Interstrand Cross-Links in the 5′-CpG-3′ Sequence †Conformational Interconversion of the trans -4-Hydroxynonenal-Derived (6 S ,8 R ,11 S ) 1, N 2 -Deoxyguanosine Adduct When Mismatched with Deoxyadenosine in DNADifferential Base Stacking Interactions Induced by Trimethylene Interstrand DNA Cross-Links in the 5′-CpG-3′ and 5′-GpC-3′ Sequence ContextsFormation of a N 2 -dG: N 2 -dG Carbinolamine DNA Cross-link by the trans -4-Hydroxynonenal-Derived (6 S ,8 R ,11 S ) 1, N 2 -dG AdductReplication Bypass of the trans -4-Hydroxynonenal-Derived (6 S ,8 R ,11 S )-1, N 2 -Deoxyguanosine DNA Adduct by the Sulfolobus solfataricus DNA Polymerase IVDeoxyguanosine forms a bis-adduct with E,E-muconaldehyde, an oxidative metabolite of benzene: implications for the carcinogenicity of benzeneRepair kinetics of trans-4-hydroxynonenal-induced cyclic 1,N2-propanodeoxyguanine DNA adducts by human cell nuclear extractsBiological properties of single chemical-DNA adducts: a twenty year perspectiveReplication and repair of a reduced 2΄-deoxyguanosine-abasic site interstrand cross-link in human cells.γ-Hydroxy-1,N2-propano-2'-deoxyguanosine DNA adduct conjugates the N-terminal amine of the KWKK peptide via a carbinolamine linkage.In vivo detection of a novel endogenous etheno-DNA adduct derived from arachidonic acid and the effects of antioxidants on its formation.Replication past a trans-4-hydroxynonenal minor-groove adduct by the sequential action of human DNA polymerases iota and kappa.Site specific synthesis and polymerase bypass of oligonucleotides containing a 6-hydroxy-3,5,6,7-tetrahydro-9H-imidazo[1,2-a]purin-9-one base, an intermediate in the formation of 1,N2-etheno-2'-deoxyguanosine.Site-specific synthesis of oligonucleotides containing malondialdehyde adducts of deoxyguanosine and deoxyadenosine via a postsynthetic modification strategy.Synthesis of the four stereoisomers of 2,3-epoxy-4-hydroxynonanal and their reactivity with deoxyguanosine.Chemistry and biology of DNA containing 1,N(2)-deoxyguanosine adducts of the alpha,beta-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal.DNA cross-link induced by trans-4-hydroxynonenal.Chemistry and structural biology of DNA damage and biological consequencesWhat is the DNA repair defect underlying Fanconi anemia?Formation of deoxyguanosine cross-links from calf thymus DNA treated with acrolein and 4-hydroxy-2-nonenal.Spectroscopic characterization of interstrand carbinolamine cross-links formed in the 5'-CpG-3' sequence by the acrolein-derived gamma-OH-1,N2-propano-2'-deoxyguanosine DNA adduct.Rearrangement of the (6S,8R,11S) and (6R,8S,11R) exocyclic 1,N2-deoxyguanosine adducts of trans-4-hydroxynonenal to N2-deoxyguanosine cyclic hemiacetal adducts when placed complementary to cytosine in duplex DNA.Stereospecific formation of the (R)-gamma-hydroxytrimethylene interstrand N2-dG:N2-dG cross-link arising from the gamma-OH-1,N2-propano-2'-deoxyguanosine adduct in the 5'-CpG-3' DNA sequence.Simplified synthesis of individual stereoisomers of the 4-hydroxynonenal adducts of deoxyguanosineRepair kinetics of acrolein- and (E)-4-hydroxy-2-nonenal-derived DNA adducts in human colon cell extracts.Interstrand DNA cross-links induced by alpha,beta-unsaturated aldehydes derived from lipid peroxidation and environmental sources.Stereoselective Substrate-Controlled Asymmetric Syntheses of both 2,5-cis- and 2,5-trans-Tetrahydrofuranoid Oxylipids: Stereodivergent Intramolecular Amide Enolate Alkylation.
P2860
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P2860
Site-specific synthesis and reactivity of oligonucleotides containing stereochemically defined 1,N2-deoxyguanosine adducts of the lipid peroxidation product trans-4-hydroxynonenal.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
Site-specific synthesis and re ...... roduct trans-4-hydroxynonenal.
@en
type
label
Site-specific synthesis and re ...... roduct trans-4-hydroxynonenal.
@en
prefLabel
Site-specific synthesis and re ...... roduct trans-4-hydroxynonenal.
@en
P2093
P356
P1476
Site-specific synthesis and re ...... product trans-4-hydroxynonenal
@en
P2093
Ivan D Kozekov
Thomas M Harris
P304
P356
10.1021/JA0288800
P407
P577
2003-05-01T00:00:00Z