The cytoplasmic domain of the alpha-subunit of glycoprotein (GP) Ib mediates attachment of the entire GP Ib-IX complex to the cytoskeleton and regulates von Willebrand factor-induced changes in cell morphology.
about
Interaction of Bruton's tyrosine kinase and protein kinase Ctheta in platelets. Cross-talk between tyrosine and serine/threonine kinasesHuman beta-filamin is a new protein that interacts with the cytoplasmic tail of glycoprotein IbalphaCytoskeletal protein ABP-280 directs the intracellular trafficking of furin and modulates proprotein processing in the endocytic pathwayActin dynamics in plateletsPlatelet activation by von Willebrand factor requires coordinated signaling through thromboxane A2 and Fc gamma IIA receptorInhibition of cytoskeletal assembly by cytochalasin B prevents signaling through tyrosine phosphorylation and secretion triggered by collagen but not by thrombinBiosynthesis and intracellular post-translational processing of normal and mutant platelet glycoprotein GPIb-IXGeneration and rescue of a murine model of platelet dysfunction: the Bernard-Soulier syndromeProteasome proteolysis supports stimulated platelet function and thrombosisThe cytoplasmic domain of the platelet glycoprotein Ibalpha is phosphorylated at serine 609.A megakaryocyte with no platelets: anti-platelet antibodies, apoptosis, and platelet production.Regulation of glycoprotein Ib-IX-von Willebrand factor interaction by cAMP-dependent protein kinase-mediated phosphorylation at Ser 166 of glycoprotein Ib(beta).GPIbα regulates platelet size by controlling the subcellular localization of filaminAnalysis of the roles of 14-3-3 in the platelet glycoprotein Ib-IX-mediated activation of integrin alpha(IIb)beta(3) using a reconstituted mammalian cell expression modelAdhesive properties of the isolated amino-terminal domain of platelet glycoprotein Ibalpha in a flow field14-3-3ζ regulates the mitochondrial respiratory reserve linked to platelet phosphatidylserine exposure and procoagulant function.Membrane skeleton orchestrates the platelet glycoprotein (GP) Ib-IX complex clustering and signaling.Interaction between platelet glycoprotein Ibalpha and filamin-1 is essential for glycoprotein Ib/IX receptor anchorage at high shear.Novel heterozygous missense mutation in the platelet glycoprotein Ib beta gene associated with isolated giant platelet disorder.Identification of the region in actin-binding protein that binds to the cytoplasmic domain of glycoprotein IBalpha.Identification of a unique filamin A binding region within the cytoplasmic domain of glycoprotein Ibalpha.Regulation of von Willebrand factor binding to the platelet glycoprotein Ib-IX by a membrane skeleton-dependent inside-out signal.Identification and characterisation of a platelet GPIb/V/IX-like complex on human breast cancers: implications for the metastatic process.14-3-3 zeta mediates integrin-induced activation of Cdc42 and Rac. Platelet glycoprotein Ib-IX regulates integrin-induced signaling by sequestering 14-3-3 zeta.Signaling role for phospholipase C gamma 2 in platelet glycoprotein Ib alpha calcium flux and cytoskeletal reorganization. Involvement of a pathway distinct from FcR gamma chain and Fc gamma RIIA.Glycoprotein Ib-mediated platelet activation. A signalling pathway triggered by thrombin.The von Willebrand factor-glycoprotein Ib/V/IX interaction induces actin polymerization and cytoskeletal reorganization in rolling platelets and glycoprotein Ib/V/IX-transfected cells.
P2860
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P2860
The cytoplasmic domain of the alpha-subunit of glycoprotein (GP) Ib mediates attachment of the entire GP Ib-IX complex to the cytoskeleton and regulates von Willebrand factor-induced changes in cell morphology.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
The cytoplasmic domain of the ...... ed changes in cell morphology.
@en
type
label
The cytoplasmic domain of the ...... ed changes in cell morphology.
@en
prefLabel
The cytoplasmic domain of the ...... ed changes in cell morphology.
@en
P2093
P2860
P356
P1476
The cytoplasmic domain of the ...... ed changes in cell morphology.
@en
P2093
P2860
P304
11581-11587
P356
10.1074/JBC.271.19.11581
P407
P577
1996-05-01T00:00:00Z