miR-30-5p functions as a tumor suppressor and novel therapeutic tool by targeting the oncogenic Wnt/β-catenin/BCL9 pathway.
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Multiple myeloma cancer stem cellsMicroRNAs: Novel Crossroads between Myeloma Cells and the Bone Marrow MicroenvironmentThe crosstalk between microRNAs and the Wnt/β-catenin signaling pathway in cancerIdentification of miRNA-mRNA Modules in Colorectal Cancer Using Rough Hypercuboid Based Supervised ClusteringCrosstalk between microRNA30a/b/c/d/e-5p and the canonical Wnt pathway: implications for multiple myeloma therapyMiRNA-30a inhibits AECs-II apoptosis by blocking mitochondrial fission dependent on Drp-1.Landscape of expression profiles in esophageal carcinoma by The Cancer Genome Atlas data.MiR-30b suppresses tumor migration and invasion by targeting EIF5A2 in gastric cancerHigh-throughput sequencing reveals differential expression of miRNAs in prehierarchal follicles of laying and brooding geese.The Cyclophilin A-CD147 complex promotes the proliferation and homing of multiple myeloma cells.Targeting the miR-221-222/PUMA/BAK/BAX Pathway Abrogates Dexamethasone Resistance in Multiple Myeloma.Selective targeting of IRF4 by synthetic microRNA-125b-5p mimics induces anti-multiple myeloma activity in vitro and in vivo.Characterization of exosomal RNAs derived from human gastric cancer cells by deep sequencing.HDAC inhibitor AR-42 decreases CD44 expression and sensitizes myeloma cells to lenalidomideBCL9, a coactivator for Wnt/β-catenin transcription, is targeted by miR-30c and is associated with prostate cancer progression.MicroRNA-30 inhibits neointimal hyperplasia by targeting Ca(2+)/calmodulin-dependent protein kinase IIδ (CaMKIIδ)Overexpression of miR-30a in lung adenocarcinoma A549 cell line inhibits migration and invasion via targeting EYA2miR-30e controls DNA damage-induced stress responses by modulating expression of the CDK inhibitor p21WAF1/CIP1 and caspase-3.A regulatory circuit of miR-125b/miR-20b and Wnt signalling controls glioblastoma phenotypes through FZD6-modulated pathways.Hypoxia activates Wnt/β-catenin signaling by regulating the expression of BCL9 in human hepatocellular carcinoma.Properties and feasibility of using cancer stem cells in clinical cancer treatment.CD73/NT5E is a target of miR-30a-5p and plays an important role in the pathogenesis of non-small cell lung cancer.The iron chelator deferasirox induces apoptosis by targeting oncogenic Pyk2/β-catenin signaling in human multiple myeloma.MiR-30c protects diabetic nephropathy by suppressing epithelial-to-mesenchymal transition in db/db mice.miR-30a radiosensitizes non-small cell lung cancer by targeting ATF1 that is involved in the phosphorylation of ATM.The microRNA regulatory network: a far-reaching approach to the regulate the Wnt signaling pathway in number of diseases.miRNAs in multiple myeloma--a survival relevant complex regulator of gene expressionUrinary MicroRNA-30c-5p and MicroRNA-192-5p as potential biomarkers of ischemia-reperfusion-induced kidney injury.TGF-β induces miR-30d down-regulation and podocyte injury through Smad2/3 and HDAC3-associated transcriptional repression.BMP9-induced osteogenic differentiation is partially inhibited by miR-30a in the mesenchymal stem cell line C3H10T1/2.MicroRNA-153 promotes Wnt/β-catenin activation in hepatocellular carcinoma through suppression of WWOX.The miR-30 family: Versatile players in breast cancer.Role of epigenetics-microRNA axis in drug resistance of multiple myeloma.miR-30a acts as a tumor suppressor by double-targeting COX-2 and BCL9 in H. pylori gastric cancer models.miR-135b Stimulates Osteosarcoma Recurrence and Lung Metastasis via Notch and Wnt/β-Catenin Signaling.Identification of four potential predicting miRNA biomarkers for multiple myeloma from published datasets.miR‑30c suppresses prostate cancer survival by targeting the ASF/SF2 splicing factor oncoprotein.Screening and identification of critical transcription factors involved in the protection of cardiomyocytes against hydrogen peroxide-induced damage by Yixin-shu.Structure-Based Design of 1,4-Dibenzoylpiperazines as β-Catenin/B-Cell Lymphoma 9 Protein-Protein Interaction Inhibitors.Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist Liraglutide Alters Bone Marrow Exosome-Mediated miRNA Signal Pathways in Ovariectomized Rats with Type 2 Diabetes.
P2860
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P2860
miR-30-5p functions as a tumor suppressor and novel therapeutic tool by targeting the oncogenic Wnt/β-catenin/BCL9 pathway.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
@zh
2014年學術文章
@zh-hant
name
miR-30-5p functions as a tumor ...... ic Wnt/β-catenin/BCL9 pathway.
@en
type
label
miR-30-5p functions as a tumor ...... ic Wnt/β-catenin/BCL9 pathway.
@en
prefLabel
miR-30-5p functions as a tumor ...... ic Wnt/β-catenin/BCL9 pathway.
@en
P2093
P2860
P1433
P1476
miR-30-5p functions as a tumor ...... ic Wnt/β-catenin/BCL9 pathway.
@en
P2093
Bryan Ciccarelli
Daniel Brooks
Geraldine Pinkus
Jian-Jun Zhao
Jianguo Tao
Jianhong Lin
Kenneth Anderson
Kohichi Takada
P2860
P304
P356
10.1158/0008-5472.CAN-13-3311-T
P407
P577
2014-03-05T00:00:00Z