Mutagenesis in mammalian cells induced by triple helix formation and transcription-coupled repair.
about
Mismatch repair participates in error-free processing of DNA interstrand crosslinks in human cells.Therapeutic modulation of endogenous gene function by agents with designed DNA-sequence specificitiesTriplex-induced recombination and repair in the pyrimidine motif.Triplex targeted genomic crosslinks enter separable deletion and base substitution pathwaysOligonucleotide-directed mutagenesis for precision gene editingThe hidden side of unstable DNA repeats: Mutagenesis at a distanceMolecular cloning and characterization of Saccharomyces cerevisiae RAD28, the yeast homolog of the human Cockayne syndrome A (CSA) geneOligo/polynucleotide-based gene modification: strategies and therapeutic potentialHypermutation of immunoglobulin genes in memory B cells of DNA repair-deficient miceDisruption of Higher Order DNA Structures in Friedreich's Ataxia (GAA)n Repeats by PNA or LNA TargetingTranscription-coupled DNA repair: two decades of progress and surprisesTriplex-induced recombination in human cell-free extracts. Dependence on XPA and HsRad51.Detection and determination of oligonucleotide triplex formation-mediated transcription-coupled DNA repair in HeLa nuclear extracts.Targeted correction of an episomal gene in mammalian cells by a short DNA fragment tethered to a triplex-forming oligonucleotide.Triple-helix formation induces recombination in mammalian cells via a nucleotide excision repair-dependent pathway.Site-directed recombination via bifunctional PNA-DNA conjugates.Spatially localized generation of nucleotide sequence-specific DNA damagePsoralen interstrand cross-link repair is specifically altered by an adjacent triple-stranded structureHuman XPA and RPA DNA repair proteins participate in specific recognition of triplex-induced helical distortionsSelection and characterization of RNAs that relieve transcriptional interference in Escherichia coli.Exploring the reasons for the large density of triplex-forming oligonucleotide target sequences in the human regulatory regionsTargeted correction of a thalassemia-associated beta-globin mutation induced by pseudo-complementary peptide nucleic acidsMismatch repair and nucleotide excision repair proteins cooperate in the recognition of DNA interstrand crosslinks.Progressive GAA.TTC repeat expansion in human cell lines.Improved bioactivity of G-rich triplex-forming oligonucleotides containing modified guanine bases.Understanding oligonucleotide-mediated inhibition of gene expression in Xenopus laevis oocytes.Peptide conjugates for chromosomal gene targeting by triplex-forming oligonucleotidesBlocking transcription of the human rhodopsin gene by triplex-mediated DNA photocrosslinkingTargeting and processing of site-specific DNA interstrand crosslinks.Mutation analysis of the entire PKD1 gene: genetic and diagnostic implicationsPeptide nucleic acids: versatile tools for gene therapy strategies.Mitotic recombination in patients with ichthyosis causes reversion of dominant mutations in KRT10In vivo and in vitro studies of immunoglobulin gene somatic hypermutation.Triplex technology in studies of DNA damage, DNA repair, and mutagenesisManipulating the mammalian genome by homologous recombinationTriple helical DNA in a duplex context and base pair opening.DNA binding and antigene activity of a daunomycin-conjugated triplex-forming oligonucleotide targeting the P2 promoter of the human c-myc gene.Triplex-forming molecules: from concepts to applications.Replication fork stalling and checkpoint activation by a PKD1 locus mirror repeat polypurine-polypyrimidine (Pu-Py) tract.Effect of third strand composition on the triple helix formation: purine versus pyrimidine oligodeoxynucleotides
P2860
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P2860
Mutagenesis in mammalian cells induced by triple helix formation and transcription-coupled repair.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Mutagenesis in mammalian cells ...... transcription-coupled repair.
@en
type
label
Mutagenesis in mammalian cells ...... transcription-coupled repair.
@en
prefLabel
Mutagenesis in mammalian cells ...... transcription-coupled repair.
@en
P2093
P1433
P1476
Mutagenesis in mammalian cells ...... transcription-coupled repair.
@en
P2093
P304
P356
10.1126/SCIENCE.271.5250.802
P407
P577
1996-02-01T00:00:00Z