Construction of a type 1 human immunodeficiency virus that maintains a primer binding site complementary to tRNA(His).
about
Efficient encapsidation of human immunodeficiency virus type 1 vectors and further characterization of cis elements required for encapsidationRole of the DIS hairpin in replication of human immunodeficiency virus type 1Preferences for the selection of unique tRNA primers revealed from analysis of HIV-1 replication in peripheral blood mononuclear cellsAnti-HIV-1 activity of anti-TAR polyamide nucleic acid conjugated with various membrane transducing peptides.The structure of the human tRNALys3 anticodon bound to the HIV genome is stabilized by modified nucleosides and adjacent mismatch base pairsPrimer tRNAs for reverse transcriptionReplication of avian sarcoma virus in vivo requires an interaction between the viral RNA and the TpsiC loop of the tRNA(Trp) primerRegulation of virus release by the macrophage-tropic human immunodeficiency virus type 1 AD8 isolate is redundant and can be controlled by either Vpu or Env.Human immunodeficiency virus type 1 integrase protein promotes reverse transcription through specific interactions with the nucleoprotein reverse transcription complex.The nucleocapsid protein specifically anneals tRNALys-3 onto a noncomplementary primer binding site within the HIV-1 RNA genome in vitro.Interactions between Ty1 retrotransposon RNA and the T and D regions of the tRNA(iMet) primer are required for initiation of reverse transcription in vivo.Reverse transcription of a self-primed retrotransposon requires an RNA structure similar to the U5-IR stem-loop of retroviruses.Changes in Rous sarcoma virus RNA secondary structure near the primer binding site upon tRNATrp primer annealing.Mutation of the methylated tRNA(Lys)(3) residue A58 disrupts reverse transcription and inhibits replication of human immunodeficiency virus type 1.Structural basis for the specificity of the initiation of HIV-1 reverse transcription.A succession of mechanisms stimulate efficient reconstituted HIV-1 minus strand strong stop DNA transferInitiation of HIV-2 reverse transcription: a secondary structure model of the RNA-tRNA(Lys3) duplex.Structural and functional properties of the HIV-1 RNA-tRNA(Lys)3 primer complex annealed by the nucleocapsid protein: comparison with the heat-annealed complexInhibition of human immunodeficiency virus type 1 replication with artificial transcription factors targeting the highly conserved primer-binding site.Two step synthesis of (-) strong-stop DNA by avian and murine reverse transcriptases in vitro.The primer binding site on the RNA genome of human and simian immunodeficiency viruses is flanked by an upstream hairpin structure.Mutational analysis of the tRNA3Lys/HIV-1 RNA (primer/template) complex.The Interaction between tRNA(Lys) 3 and the primer activation signal deciphered by NMR spectroscopy.The tRNA primer activation signal in the human immunodeficiency virus type 1 genome is important for initiation and processive elongation of reverse transcriptiontRNA isoacceptor preference prior to retrovirus Gag-Pol junction links primer selection and viral translation.Effects of modifying the tRNA(3Lys) anticodon on the initiation of human immunodeficiency virus type 1 reverse transcriptionA conserved hairpin motif in the R-U5 region of the human immunodeficiency virus type 1 RNA genome is essential for replicationThe importance of the A-rich loop in human immunodeficiency virus type 1 reverse transcription and infectivity.Identification of sequences downstream of the primer binding site that are important for efficient replication of human immunodeficiency virus type 1.Nucleotide substitutions within U5 are critical for efficient reverse transcription of human immunodeficiency virus type 1 with a primer binding site complementary to tRNA(His)Placement of tRNA primer on the primer-binding site requires pol gene expression in avian but not murine retroviruses.Multiple biological roles associated with the Rous sarcoma virus 5' untranslated RNA U5-IR stem and loop.Binding and kinetic properties of HIV-1 reverse transcriptase markedly differ during initiation and elongation of reverse transcription.Forced selection of tRNA(Glu) reveals the importance of two adenosine-rich RNA loops within the U5-PBS for SIV(smmPBj) replication.Prospects for antisense peptide nucleic acid (PNA) therapies for HIVSynthetic tRNALys,3 as the replication primer for the HIV-1HXB2 and HIV-1Mal genomes.Frequent dual initiation in human immunodeficiency virus-based vectors containing two primer-binding sites: a quantitative in vivo assay for function of initiation complexes.Destabilization of tRNA3(Lys) from the primer-binding site of HIV-1 genome by anti-A loop polyamide nucleotide analogHuman immunodeficiency virus type-1 reverse transcription can be inhibited in vitro by oligonucleotides that target both natural and synthetic tRNA primers.A structured RNA motif is involved in correct placement of the tRNA(3)(Lys) primer onto the human immunodeficiency virus genome.
P2860
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P2860
Construction of a type 1 human immunodeficiency virus that maintains a primer binding site complementary to tRNA(His).
description
1996 nî lūn-bûn
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1996年の論文
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1996年学术文章
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1996年学术文章
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1996年学术文章
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1996年学术文章
@zh-my
1996年学术文章
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1996年學術文章
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1996年學術文章
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1996年學術文章
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name
Construction of a type 1 human ...... te complementary to tRNA(His).
@en
type
label
Construction of a type 1 human ...... te complementary to tRNA(His).
@en
prefLabel
Construction of a type 1 human ...... te complementary to tRNA(His).
@en
P2093
P2860
P1433
P1476
Construction of a type 1 human ...... te complementary to tRNA(His).
@en
P2093
C D Morrow
J K Wakefield
P2860
P304
P407
P577
1996-02-01T00:00:00Z