PTK7/Otk interacts with Wnts and inhibits canonical Wnt signalling.
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Ptk7 and Mcc, Unfancied Components in Non-Canonical Wnt Signaling and CancerThe role of Ryk and Ror receptor tyrosine kinases in Wnt signal transductionWnt and planar cell polarity signaling in cystic renal diseaseThe PTK7-related transmembrane proteins off-track and off-track 2 are co-receptors for Drosophila Wnt2 required for male fertilityA PTK7/Ror2 Co-Receptor Complex Affects Xenopus Neural Crest MigrationMaternal-fetal unit interactions and eutherian neocortical development and evolutionDistinct apical and basolateral mechanisms drive planar cell polarity-dependent convergent extension of the mouse neural plate.Restoration of WNT4 inhibits cell growth in leukemia-derived cell linesProtein-tyrosine pseudokinase 7 (PTK7) directs cancer cell motility and metastasis.A meta-analysis of lung cancer gene expression identifies PTK7 as a survival gene in lung adenocarcinomaProtein tyrosine kinase 7 (PTK7) as a predictor of lymph node metastases and a novel prognostic biomarker in patients with prostate cancer.ptk7 mutant zebrafish models of congenital and idiopathic scoliosis implicate dysregulated Wnt signalling in disease.Comparative sequencing analysis reveals high genomic concordance between matched primary and metastatic colorectal cancer lesionsGenome-wide association studies reveal a simple genetic basis of resistance to naturally coevolving viruses in Drosophila melanogasterHigh expression of protein tyrosine kinase 7 significantly associates with invasiveness and poor prognosis in intrahepatic cholangiocarcinoma.Off-track takes Frizzled off the canonical pathPlanar polarity: A new player in both lung development and diseaseRegulation of distinct branches of the non-canonical Wnt-signaling network in Xenopus dorsal marginal zone explantsThe cytosolic domain of protein-tyrosine kinase 7 (PTK7), generated from sequential cleavage by a disintegrin and metalloprotease 17 (ADAM17) and γ-secretase, enhances cell proliferation and migration in colon cancer cellsExploring Mouse Protein Function via Multiple Approaches.PTK7: a new biomarker for immunophenotypic characterization of maturing T cells and T cell acute lymphoblastic leukemiaThe PTK7 and ROR2 Protein Receptors Interact in the Vertebrate WNT/Planar Cell Polarity (PCP) Pathway.Insights into ectodomain shedding and processing of protein-tyrosine pseudokinase 7 (PTK7)Receptor tyrosine kinases in Drosophila development.Effects of membrane trafficking on signaling by receptor tyrosine kinases.Planar cell polarity in kidney development and disease.Integration of anterior neural plate patterning and morphogenesis by the Wnt signaling pathway.Planar cell polarity of the kidney.Vertebrate Axial Patterning: From Egg to Asymmetry.Transforming growth factor-β1 induces invasion ability of HSC-4 human oral squamous cell carcinoma cells through the Slug/Wnt-5b/MMP-10 signalling axis.Downstream signaling and genome-wide regulatory effects of PTK7 pseudokinase and its proteolytic fragments in cancer cells.Role of the planar cell polarity gene Protein tyrosine kinase 7 in neural tube defects in humans.An embryonic system to assess direct and indirect Wnt transcriptional targetsWnt, Ptk7, and FGFRL expression gradients control trunk positional identity in planarian regeneration.PTK7 Faces the Wnt in Development and Disease.PTK7 is a novel oncogenic target for esophageal squamous cell carcinoma.Luminescence switch-on detection of protein tyrosine kinase-7 using a G-quadruplex-selective probe.Wnt6 maintains anterior escort cells as an integral component of the germline stem cell niche.Biphasic regulation of tumorigenesis by PTK7 expression level in esophageal squamous cell carcinoma.PTK7 as a novel marker for favorable gastric cancer patient survival
P2860
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P2860
PTK7/Otk interacts with Wnts and inhibits canonical Wnt signalling.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
PTK7/Otk interacts with Wnts and inhibits canonical Wnt signalling.
@en
type
label
PTK7/Otk interacts with Wnts and inhibits canonical Wnt signalling.
@en
prefLabel
PTK7/Otk interacts with Wnts and inhibits canonical Wnt signalling.
@en
P2093
P2860
P356
P1433
P1476
PTK7/Otk interacts with Wnts and inhibits canonical Wnt signalling.
@en
P2093
Annette Borchers
Hanna Peradziryi
Martina Podleschny
Nicholas S Tolwinski
Nicole A Kaplan
Peter Wehner
Xiaoping Liu
P2860
P304
P356
10.1038/EMBOJ.2011.236
P407
P577
2011-07-19T00:00:00Z