A robust assay for alternative lengthening of telomeres in tumors shows the significance of alternative lengthening of telomeres in sarcomas and astrocytomas.
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Spanning the genomics era: the vital role of a single institution biorepository for childhood cancer research over a decadeVariations in telomere maintenance and the role of telomerase inhibition in gastrointestinal cancerOsteosarcoma Genetics and Epigenetics: Emerging Biology and Candidate TherapiesTelomere regulation in pluripotent stem cellsModeling human endothelial cell transformation in vascular neoplasiasAlternative mechanisms of telomere lengthening: permissive mutations, DNA repair proteins and tumorigenic progressionThe Role of ATRX in the Alternative Lengthening of Telomeres (ALT) PhenotypeGenetic Inactivation of ATRX Leads to a Decrease in the Amount of Telomeric Cohesin and Level of Telomere Transcription in Human Glioma CellsPML bodies provide an important platform for the maintenance of telomeric chromatin integrity in embryonic stem cellsAssessing telomeric DNA content in pediatric cancers using whole-genome sequencing data.TERT promoter hotspot mutations are recurrent in myxoid liposarcomas but rare in other soft tissue sarcoma entitiesPrognostic relevance of ALT-associated markers in liposarcoma: a comparative analysis.Doxorubicin resistance in a novel in vitro model of human pleomorphic liposarcoma associated with alternative lengthening of telomeres.Epigenetic Regulation of Telomere Maintenance for Therapeutic Interventions in Gliomas.HP1-mediated formation of alternative lengthening of telomeres-associated PML bodies requires HIRA but not ASF1a.The CDKN2A G500 allele is more frequent in GBM patients with no defined telomere maintenance mechanism tumors and is associated with poorer survival.The role of post-translational modifications in fine-tuning BLM helicase function during DNA repairMultiple Mechanisms Contribute To Telomere Maintenance.Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway.Pilocytic astrocytomas have telomere-associated promyelocytic leukemia bodies without alternatively lengthened telomeres.Telomerase-dependent and independent telomere maintenance and its clinical implications in medullary thyroid carcinoma.Telomere maintenance mechanisms in cancer: clinical implicationsExtreme telomere length dimorphism in the Tasmanian devil and related marsupials suggests parental control of telomere lengthLoss of wild-type ATRX expression in somatic cell hybrids segregates with activation of Alternative Lengthening of Telomeres.The genetics of osteosarcoma.A preclinical mouse model of glioma with an alternative mechanism of telomere maintenance (ALT).Telomere length is related to alternative splice patterns of telomerase in thyroid tumors.Prevalence of the alternative lengthening of telomeres telomere maintenance mechanism in human cancer subtypes.Telomere length variation: A potential new telomere biomarker for lung cancer risk.Expression of telomeres in astrocytoma WHO grade 2 to 4: TERRA level correlates with telomere length, telomerase activity, and advanced clinical grade.Expression Pattern of Alternative Splicing Variants of Human Telomerase Reverse Transcriptase (hTERT) in Cancer Cell Lines Was not Associated with the Origin of the CellsCorrelations of telomere length, P53 mutation, and chromosomal translocation in soft tissue sarcomasModulation of telomeres in alternative lengthening of telomeres type I like human cells by the expression of werner protein and telomerase.Telomere maintenance mechanisms in malignant peripheral nerve sheath tumors: expression and prognostic relevanceStrong association between long and heterogeneous telomere length in blood lymphocytes and bladder cancer risk in Egyptian.Targeted next-generation sequencing of cancer genes identified frequent TP53 and ATRX mutations in leiomyosarcoma.Human sarcomas are mosaic for telomerase-dependent and telomerase-independent telomere maintenance mechanisms: implications for telomere-based therapiesAlternative lengthening of telomeres in normal mammalian somatic cells.Detection of alternative lengthening of telomeres by telomere quantitative PCR.Prognostic significance of telomerase-associated parameters in glioblastoma: effect of patient age.
P2860
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P2860
A robust assay for alternative lengthening of telomeres in tumors shows the significance of alternative lengthening of telomeres in sarcomas and astrocytomas.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
A robust assay for alternative ...... in sarcomas and astrocytomas.
@en
type
label
A robust assay for alternative ...... in sarcomas and astrocytomas.
@en
prefLabel
A robust assay for alternative ...... in sarcomas and astrocytomas.
@en
P2093
P1476
A robust assay for alternative ...... s in sarcomas and astrocytomas
@en
P2093
Bruce G Robinson
David A Jellinek
Diana L Learoyd
Janice A Royds
Jeremy D Henson
Jinyoung Yoo
Jonathan A Hannay
Paul D Stalley
Raphael E Pollock
P304
P407
P577
2005-01-01T00:00:00Z