FAF1 suppresses IkappaB kinase (IKK) activation by disrupting the IKK complex assembly. - Wikidata - awgldk - TriplyDB

FAF1 suppresses IkappaB kinase (IKK) activation by disrupting the IKK complex assembly.

FAF1 suppresses IkappaB kinase (IKK) activation by disrupting the IKK complex assembly.

http://www.wikidata.org/entity/Q38504848

about

The NLRP12 Pyrin Domain: Structure, Dynamics, and Functional Insights UBXD Proteins: A Family of Proteins with Diverse Functions in Cancer FAS-associated factor-1 positively regulates type I interferon response to RNA virus infection by targeting NLRX1.VAPB/ALS8 interacts with FFAT-like proteins including the p97 cofactor FAF1 and the ASNA1 ATPase p97-containing complexes in proliferation control and cancer: emerging culprits or guilt by association?Ubiquitin-associated (UBA) domain in human Fas associated factor 1 inhibits tumor formation by promoting Hsp70 degradation Fas-associated factor (Faf1) is a novel CD40 interactor that regulates CD40-induced NF-κB activation via a negative feedback loop.Ubiquitin-associated domain-containing ubiquitin regulatory X (UBX) protein UBXN1 is a negative regulator of nuclear factor κB (NF-κB) signaling Fas-associated factor 1 is a scaffold protein that promotes β-transducin repeat-containing protein (β-TrCP)-mediated β-catenin ubiquitination and degradation Complex of Fas-associated factor 1 (FAF1) with valosin-containing protein (VCP)-Npl4-Ufd1 and polyubiquitinated proteins promotes endoplasmic reticulum-associated degradation (ERAD)UAS domain of Ubxd8 and FAF1 polymerizes upon interaction with long-chain unsaturated fatty acids Activated TNF-alpha/NF-kappaB signaling via down-regulation of Fas-associated factor 1 in asbestos-induced mesotheliomas from Arf knockout mice Uniparental disomies, homozygous deletions, amplifications, and target genes in mantle cell lymphoma revealed by integrative high-resolution whole-genome profiling.The Drosophila IMD pathway in the activation of the humoral immune response.Validation of Type 2 Diabetes Risk Variants Identified by Genome-Wide Association Studies in Northern Han Chinese.Structure and interaction of ubiquitin-associated domain of human Fas-associated factor 1.The p97-UFD1L-NPL4 protein complex mediates cytokine-induced IκBα proteolysis.FAS-associated factor 1 (FAF1): diverse functions and implications for oncogenesis.FAF1 mediates regulated necrosis through PARP1 activation upon oxidative stress leading to dopaminergic neurodegeneration Fas-associated factor 1 antagonizes Wnt signaling by promoting β-catenin degradation.Allo-antigen stimulated CD8+ T-cells suppress NF-κB and Ets-1 DNA binding activity, and inhibit phosphorylated NF-κB p65 nuclear localization in CD4+ T-cells.Crystallization and preliminary X-ray crystallographic analysis of human FAF1 UBX domain.Crystallization and preliminary X-ray crystallographic analysis of the N domain of p97/VCP in complex with the UBX domain of FAF1.Negative feedback regulation of Aurora-A via phosphorylation of Fas-associated factor-1.Fas-associated protein factor 1 is involved in meiotic resumption in mouse oocytes.FAF1 mediates necrosis through JNK1-mediated mitochondrial dysfunction leading to retinal degeneration in the ganglion cell layer upon ischemic insult

P2860

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P2860

FAF1 suppresses IkappaB kinase (IKK) activation by disrupting the IKK complex assembly.

http://www.wikidata.org/entity/Q38504848

description

2007 nî lūn-bûn

@nan

2007年の論文

@ja

2007年論文

@yue

2007年論文

@zh-hant

2007年論文

@zh-hk

2007年論文

@zh-mo

2007年論文

@zh-tw

2007年论文

@wuu

2007年论文

@zh

2007年论文

@zh-cn

name

FAF1 suppresses IkappaB kinase (IKK) activation by disrupting the IKK complex assembly.

@en

type

label

FAF1 suppresses IkappaB kinase (IKK) activation by disrupting the IKK complex assembly.

@en

prefLabel

FAF1 suppresses IkappaB kinase (IKK) activation by disrupting the IKK complex assembly.

@en

P1433

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P1476

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P698

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P356

P1433

Journal of Biological Chemistry

P1476

FAF1 suppresses IkappaB kinase (IKK) activation by disrupting the IKK complex assembly.

@en

P2093

Eunhee Kim

http://www.w3.org/2001/XMLSchema#string

Hye-In Choi

http://www.w3.org/2001/XMLSchema#string

Hyo Jeong Hong

http://www.w3.org/2001/XMLSchema#string

Ji-hyun Moon

http://www.w3.org/2001/XMLSchema#string

Jongkyeong Chung

http://www.w3.org/2001/XMLSchema#string

Ki-Sung Lee

http://www.w3.org/2001/XMLSchema#string

Min-Young Park

http://www.w3.org/2001/XMLSchema#string

P2860

Identification and characterization of human Fas associated factor 1, hFAF1

Analysis of domains in the IKKalpha and IKKbeta proteins that regulate their kinase activity

Fas-associated factor-1 mediates chemotherapeutic-induced apoptosis via death effector filament formation

Human Fas-associated factor 1, interacting with ubiquitinated proteins and valosin-containing protein, is involved in the ubiquitin-proteasome pathway

Fas-associated factor-1 inhibits nuclear factor-kappaB (NF-kappaB) activity by interfering with nuclear translocation of the RelA (p65) subunit of NF-kappaB

Fas-associated factor 1, FAF1, is a member of Fas death-inducing signaling complex

Human Fas-associated factor 1 interacts with heat shock protein 70 and negatively regulates chaperone activity

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

A Fas-associated protein factor, FAF1, potentiates Fas-mediated apoptosis

Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice

P304

27572-27577

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P31

scholarly article

P356

10.1074/JBC.C700106200

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P407

P433

38

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P478

282

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P577

2007-08-07T00:00:00Z

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P698

17684021

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