Targeting acute ischemic stroke with a calcium-sensitive opener of maxi-K potassium channels.
about
Discovery, Synthesis, and Structure–Activity Relationship of a Series of N -Aryl-bicyclo[2.2.1]heptane-2-carboxamides: Characterization of ML213 as a Novel KCNQ2 and KCNQ4 Potassium Channel OpenerNeuroprotection for ischemic stroke: past, present and futureInactivation as a new regulatory mechanism for neuronal Kv7 channelsOxidative Stress and Maxi Calcium-Activated Potassium (BK) ChannelsBK channels: multiple sensors, one activation gateBMS-204352: a potassium channel opener developed for the treatment of strokeStimulatory action of internal protons on Slo1 BK channelsActivation of BKca channels mediates hippocampal neuronal death after reoxygenation and reperfusion17 Beta-estradiol prevents focal cerebral ischemic damages via activation of Akt and CREB in association with reduced PTEN phosphorylation in ratsBK Channels in the Central Nervous System.Baifuzi reduces transient ischemic brain damage through an interaction with the STREX domain of BKCa channels.SK2 channels are neuroprotective for ischemia-induced neuronal cell deathHigh performance liquid chromatographic-mass spectrometric assay for the quantitation of BMS-204352 in dog K(3)EDTA plasma.Down-regulation of BK channel expression in the pilocarpine model of temporal lobe epilepsy.Zn2+ activates large conductance Ca2+-activated K+ channel via an intracellular domain.Neuronal Ca2+-activated K+ channels limit brain infarction and promote survivalCritical role of large-conductance calcium- and voltage-activated potassium channels in leptin-induced neuroprotection of N-methyl-d-aspartate-exposed cortical neurons.Antecedent ethanol attenuates cerebral ischemia/reperfusion-induced leukocyte-endothelial adhesive interactions and delayed neuronal death: role of large conductance, Ca2+-activated K+ channelsLeptin counteracts the hypoxia-induced inhibition of spontaneously firing hippocampal neurons: a microelectrode array study.Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by a BKCa channel opener molecule.The SK3/K(Ca)2.3 potassium channel is a new cellular target for edelfosine.Pharmacological interventions for stroke: failures and future.Augmentation of M-type (KCNQ) potassium channels as a novel strategy to reduce stroke-induced brain injury.Up-regulation of A-type potassium currents protects neurons against cerebral ischemiaThe therapeutic potential of neuronal KCNQ channel modulators.Advances in stroke therapyThe LRRC26 protein selectively alters the efficacy of BK channel activators.Molecular mechanism of pharmacological activation of BK channels.Potassium channel subtypes as molecular targets for overactive bladder and other urological disorders.Therapeutic potential of KCa3.1 blockers: recent advances and promising trends.Neuroprotection for ischemic stroke: two decades of success and failure.Multiple facets of maxi-k+ channels: the heme connection.Targeting Ion Channels: An Important Therapeutic Implication in Gastrointestinal Dysmotility in Patients With Spinal Cord InjuryComputational models of neuronal biophysics and the characterization of potential neuropharmacological targets.Novel anticonvulsant drugs targeting voltage-dependent ion channels.Vascular KCa-channels as therapeutic targets in hypertension and restenosis disease.Leptin-mediated ion channel regulation: PI3K pathways, physiological role, and therapeutic potentialTamoxifen mediated estrogen receptor activation protects against early impairment of hippocampal neuron excitability in an oxygen/glucose deprivation brain slice ischemia model.Neuroprotectants in stroke therapy.Large-conductance Ca(2+)-activated K(+) channel involvement in suppression of cerebral ischemia/reperfusion injury after electroacupuncture at Shuigou (GV26) acupoint in rats.
P2860
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P2860
Targeting acute ischemic stroke with a calcium-sensitive opener of maxi-K potassium channels.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Targeting acute ischemic strok ...... of maxi-K potassium channels.
@en
type
label
Targeting acute ischemic strok ...... of maxi-K potassium channels.
@en
prefLabel
Targeting acute ischemic strok ...... of maxi-K potassium channels.
@en
P2093
P356
P1433
P1476
Targeting acute ischemic strok ...... of maxi-K potassium channels.
@en
P2093
Boissard CG
Dworetzky SI
Gribkoff VK
Hewawasam P
Hibbard JR
P2888
P304
P356
10.1038/86546
P407
P577
2001-04-01T00:00:00Z
P5875
P6179
1022536281