The funny current has a major pacemaking role in the sinus node.
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Hyperpolarization-activated current, If, in mathematical models of rabbit sinoatrial node pacemaker cellsIon Channels in the HeartFunny channel gene mutations associated with arrhythmiasPacemaker Created in Human Ventricle by Depressing Inward-Rectifier K⁺ Current: A Simulation StudyThe importance of Ca(2+)-dependent mechanisms for the initiation of the heartbeatHierarchical clustering of ryanodine receptors enables emergence of a calcium clock in sinoatrial node cells.Mechanism of automaticity in cardiomyocytes derived from human induced pluripotent stem cells.Mechano-sensitivity of cardiac pacemaker function: pathophysiological relevance, experimental implications, and conceptual integration with other mechanisms of rhythmicity.Genetic inhibition of Na+-Ca2+ exchanger current disables fight or flight sinoatrial node activity without affecting resting heart rate.Mechanisms of beat-to-beat regulation of cardiac pacemaker cell function by Ca²⁺ cycling dynamics.Numerical Modeling Calcium and CaMKII Effects in the SA Node.Optical imaging of voltage and calcium in cardiac cells & tissuesSmall functional If current in sinoatrial pacemaker cells of the brown trout (Salmo trutta fario) heart despite strong expression of HCN channel transcripts.A Singular Role of IK1 Promoting the Development of Cardiac Automaticity during Cardiomyocyte Differentiation by IK1 -Induced Activation of Pacemaker Current.Computational analysis of the human sinus node action potential: model development and effects of mutations.Current understanding of the pathophysiological mechanisms responsible for inappropriate sinus tachycardia: role of the If "funny" current.Funny Current and Cardiac Rhythm: Insights from HCN Knockout and Transgenic Mouse ModelsAn updated computational model of rabbit sinoatrial action potential to investigate the mechanisms of heart rate modulation.Current state of the art for cardiac arrhythmia gene therapy.Ca(2+) cycling properties are conserved despite bradycardic effects of heart failure in sinoatrial node cells.9-Phenanthrol and flufenamic acid inhibit calcium oscillations in HL-1 mouse cardiomyocytes.Electrophysiological heterogeneity of pacemaker cells in rabbit intercaval region, including SA node: insights from recording multiple ion currents in each cell.Cytosolic calcium ions exert a major influence on the firing rate and maintenance of pacemaker activity in guinea-pig sinus node.Positive Feedback Mechanisms among Local Ca Releases, NCX, and ICaL Ignite Pacemaker Action Potentials.Kir2 inward rectification-controlled precise and dynamic balances between Kir2 and HCN currents initiate pacemaking activity.A gain-of-function mutation in the cardiac pacemaker HCN4 channel increasing cAMP sensitivity is associated with familial Inappropriate Sinus Tachycardia.A Loss-of-Function Mutation Associated With Familial Benign Myoclonic Epilepsy in Infancy Causes Increased Neuronal ExcitabilityCalcium transient and sodium-calcium exchange current in human versus rabbit sinoatrial node pacemaker cells
P2860
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P2860
The funny current has a major pacemaking role in the sinus node.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
The funny current has a major pacemaking role in the sinus node.
@en
type
label
The funny current has a major pacemaking role in the sinus node.
@en
prefLabel
The funny current has a major pacemaking role in the sinus node.
@en
P1433
P1476
The funny current has a major pacemaking role in the sinus node.
@en
P2093
Dario DiFrancesco
Denis Noble
P304
P356
10.1016/J.HRTHM.2011.09.021
P577
2011-09-16T00:00:00Z