Fanconi anemia: a model disease for studies on human genetics and advanced therapeutics.
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Hallmarks of progeroid syndromes: lessons from mice and reprogrammed cellsHereditary Predispositions to Myelodysplastic SyndromeMechanism and disease association of E2-conjugating enzymes: lessons from UBE2T and UBE2L3A never-ending story: the steadily growing family of the FA and FA-like genesCurrent Knowledge and Priorities for Future Research in Late Effects after Hematopoietic Cell Transplantation for Inherited Bone Marrow Failure Syndromes: Consensus Statement from the Second Pediatric Blood and Marrow Transplant Consortium InternatiAllogeneic hematopoietic stem cell transplantation for inherited bone marrow failure syndromes.Reanalysis of BRCA1/2 negative high risk ovarian cancer patients reveals novel germline risk loci and insights into missing heritability.Rescue from replication stress during mitosis.FANCA Gene Mutations with 8 Novel Molecular Changes in Indian Fanconi Anemia Patients.Fancb deficiency impairs hematopoietic stem cell function.FANCJ at the FORK.FANCD2 functions as a critical factor downstream of MiTF to maintain the proliferation and survival of melanoma cellsImpaired mitophagy in Fanconi anemia is dependent on mitochondrial fission.Maintenance of genome stability by Fanconi anemia proteins.Defects in the Fanconi Anemia Pathway in Head and Neck Cancer Cells Stimulate Tumor Cell Invasion through DNA-PK and Rac1 Signaling.Individuals with FANCM biallelic mutations do not develop Fanconi anemia, but show risk for breast cancer, chemotherapy toxicity and may display chromosome fragility.Biallelic inactivation of REV7 is associated with Fanconi anemia.Upregulated LINE-1 Activity in the Fanconi Anemia Cancer Susceptibility Syndrome Leads to Spontaneous Pro-inflammatory Cytokine Production.Distinct Metabolic Signature of Human Bladder Cancer Cells Carrying an Impaired Fanconi Anemia Tumor-Suppressor Signaling Pathway.CRISPR-Cas9 technology and its application in haematological disorders.Hereditary breast and ovarian cancer: new genes in confined pathways.Aplastic anemia and clonal evolution: germ line and somatic genetics.SNM1B/Apollo in the DNA damage response and telomere maintenanceHow I manage patients with Fanconi anaemia.Recent insights into the molecular basis of Fanconi anemia: genes, modifiers, and drivers.The Fanconi anemia DNA damage repair pathway in the spotlight for germline predisposition to colorectal cancer.Fanconi Anemia Proteins Function in Mitophagy and ImmunityInvolvement of FANCD2 in Energy Metabolism via ATP5α.A strategy for molecular diagnostics of Fanconi anemia in Brazilian patients.FANCD2 and DNA Damage.Multifunctional Fanconi proteins, inflammation and the Fanconi phenotype.V(D)J recombination process and the Pre-B to immature B-cells transition are altered in Fanca(-/-) mice.Therapeutic gene editing in CD34+ hematopoietic progenitors from Fanconi anemia patients.Accurate quantification of homologous recombination in zebrafish: brca2 deficiency as a paradigm.A homozygous FANCM mutation underlies a familial case of non-syndromic primary ovarian insufficiency.Contribution of germline deleterious variants in the RAD51 paralogs to breast and ovarian cancers.Radiation-free, alternative-donor HCT for Fanconi anemia patients: results from a prospective multi-institutional study.Fanconi Anemia Signaling and Cancer.The BRCA2 c.68-7T > A variant is not pathogenic: A model for clinical calibration of spliceogenicity.Biallelic truncating FANCM mutations cause early-onset cancer but not Fanconi anemia.
P2860
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P2860
Fanconi anemia: a model disease for studies on human genetics and advanced therapeutics.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Fanconi anemia: a model disease for studies on human genetics and advanced therapeutics.
@en
type
label
Fanconi anemia: a model disease for studies on human genetics and advanced therapeutics.
@en
prefLabel
Fanconi anemia: a model disease for studies on human genetics and advanced therapeutics.
@en
P1476
Fanconi anemia: a model disease for studies on human genetics and advanced therapeutics.
@en
P356
10.1016/J.GDE.2015.07.002
P577
2015-08-06T00:00:00Z