Fancb deficiency impairs hematopoietic stem cell function.
about
Fanconi Anemia: A DNA repair disorder characterized by accelerated decline of the hematopoietic stem cell compartment and other features of aging.Somatic mosaicism of an intragenic FANCB duplication in both fibroblast and peripheral blood cells observed in a Fanconi anemia patient leads to milder phenotype.Icraiin improves Fanconi anemia hematopoietic stem cell function through SIRT6-mediated NF-kappa B inhibition.Cell-Cycle-Specific Function of p53 in Fanconi Anemia Hematopoietic Stem and Progenitor Cell Proliferation.Studies in an Early Development Window Unveils a Severe HSC Defect in both Murine and Human Fanconi Anemia
P2860
Fancb deficiency impairs hematopoietic stem cell function.
description
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Fancb deficiency impairs hematopoietic stem cell function.
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Fancb deficiency impairs hematopoietic stem cell function.
@en
type
label
Fancb deficiency impairs hematopoietic stem cell function.
@ast
Fancb deficiency impairs hematopoietic stem cell function.
@en
prefLabel
Fancb deficiency impairs hematopoietic stem cell function.
@ast
Fancb deficiency impairs hematopoietic stem cell function.
@en
P2093
P2860
P356
P1433
P1476
Fancb deficiency impairs hematopoietic stem cell function.
@en
P2093
Amom Ruhikanta Meetei
Andrew Wilson
Ozlem Erden
Paul R Andreassen
Qishen Pang
Satoshi H Namekawa
Surya Amarachintha
P2860
P2888
P356
10.1038/SREP18127
P407
P577
2015-12-11T00:00:00Z