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Structures of a Nonribosomal Peptide Synthetase Module Bound to MbtH-Like Proteins Support a Highly Dynamic Domain ArchitectureBioinformatics Prediction of Polyketide Synthase Gene Clusters from Mycosphaerella fijiensisSticky swinging arm dynamics: studies of an acyl carrier protein domain from the mycolactone polyketide synthaseX-ray Scattering Studies of Protein Structural Dynamics.Identification and classification of known and putative antimicrobial compounds produced by a wide variety of Bacillales species.SNaPe: a versatile method to generate multiplexed protein fusions using synthetic linker peptides for in vitro applications.Nonribosomal Peptide Synthesis-Principles and Prospects.Structural and mutational analysis of the nonribosomal peptide synthetase heterocyclization domain provides insight into catalysis.Secondary Metabolites from Polar Organisms.Development of an Unnatural Amino Acid Incorporation System in the Actinobacterial Natural Product Producer Streptomyces venezuelae ATCC 15439.Bioactive natural products from novel microbial sources.Towards Precision Engineering of Canonical Polyketide Synthase Domains: Recent Advances and Future Prospects.δ-(L-α-aminoadipyl)-L-cysteinyl-D-valine synthetase (ACVS): discovery and perspectives.Biogenesis of antibiotics-viewing its history and glimpses of the future.Structural and dynamic characterization of a freestanding acyl carrier protein involved in the biosynthesis of cyclic lipopeptide antibiotics.Diversity of nature's assembly lines - recent discoveries in non-ribosomal peptide synthesis.Mining Bacterial Genomes for Secondary Metabolite Gene Clusters.Nonribosomal peptide synthetase biosynthetic clusters of ESKAPE pathogens.Strategies in megasynthase engineering - fatty acid synthases (FAS) as model proteinsManipulation of an existing crystal form unexpectedly results in interwoven packing networks with pseudo-translational symmetry.Biosynthesis of the antibiotic nonribosomal peptide penicillin in baker's yeastAn Engineered Synthetic Pathway for Discovering Nonnatural Nonribosomal Peptides in Escherichia coli.Single polysaccharide assembly protein that integrates polymerization, termination, and chain-length quality control.The Lactococcus lactis KF147 nonribosomal peptide synthetase/polyketide synthase system confers resistance to oxidative stress during growth on plant leaf tissue lysate.ClusterCAD: a computational platform for type I modular polyketide synthase design.Synthetic biology, genome mining, and combinatorial biosynthesis of NRPS-derived antibiotics: a perspective.Programmable Bio-surfaces for Biomedical Applications.FRET monitoring of a nonribosomal peptide synthetase.Diversity of Polyketide Chains Achieved by Deleting the Tailoring Genes in the Biosynthesis of Ansatrienins.Antibiotics from Gram-negative bacteria: a comprehensive overview and selected biosynthetic highlights.Fatty acid synthases: Re-engineering biofactories.Recovering Genomics Clusters of Secondary Metabolites from Lakes Using Genome-Resolved Metagenomics.Comparative genomics reveals phylogenetic distribution patterns of secondary metabolites in Amycolatopsis species.Isolation and Identification of an Anthracimycin Analogue from Nocardiopsis kunsanensis, a Halophile from a Saltern, by Genomic Mining Strategy.Natural separation of the acyl-CoA ligase reaction results in a non-adenylating enzymeSynthetic biology approaches and combinatorial biosynthesis towards heterologous lipopeptide productionEnzymatic complexes across scales
P2860
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P2860
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
The structural biology of biosynthetic megaenzymes.
@en
type
label
The structural biology of biosynthetic megaenzymes.
@en
prefLabel
The structural biology of biosynthetic megaenzymes.
@en
P2860
P356
P1476
The structural biology of biosynthetic megaenzymes.
@en
P2093
Kira J Weissman
P2860
P2888
P304
P356
10.1038/NCHEMBIO.1883
P577
2015-08-01T00:00:00Z
P6179
1040935090