Structures of G protein-coupled receptors reveal new opportunities for drug discovery.
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Nanobodies to Study G Protein-Coupled Receptor Structure and Function.Antibody Engineering & Therapeutics, the annual meeting of The Antibody Society December 7-10, 2015, San Diego, CA, USA.Structure-Based Screening of Uncharted Chemical Space for Atypical Adenosine Receptor Agonists.Structural Mapping and Functional Characterization of Zebrafish Class B G-Protein Coupled Receptor (GPCR) with Dual Ligand Selectivity towards GLP-1 and GlucagonCholesterol-dependent Conformational Plasticity in GPCR Dimers.SLC Transporters: Structure, Function, and Drug Discovery.Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists.Using random forests for assistance in the curation of G-protein coupled receptor databases.What Do Structures Tell Us About Chemokine Receptor Function and Antagonism?New winds in GPCR-based drug discovery.Molecular Docking, Molecular Dynamics, and Structure-Activity Relationship Explorations of 14-Oxygenated N-Methylmorphinan-6-ones as Potent μ-Opioid Receptor Agonists.The cubicon method for concentrating membrane proteins in the cubic mesophase.Improving virtual screening of G protein-coupled receptors via ligand-directed modeling.Insight into partial agonism by observing multiple equilibria for ligand-bound and Gs-mimetic nanobody-bound β1-adrenergic receptor.Towards high throughput GPCR crystallography: In Meso soaking of Adenosine A2A Receptor crystals.Computational Methods Used in Hit-to-Lead and Lead Optimization Stages of Structure-Based Drug Discovery.Methodologies for the Examination of Water in GPCRs.Molecular Basis of Ligand Dissociation from G Protein-Coupled Receptors and Predicting Residence Time.Trends in GPCR drug discovery: new agents, targets and indications.The GTPase Rab43 Controls the Anterograde ER-Golgi Trafficking and Sorting of GPCRs.Activation processes in ligand-activated G protein-coupled receptors: A case study of the adenosine A2A receptor.Modeling and Deorphanization of Orphan GPCRs.
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P2860
Structures of G protein-coupled receptors reveal new opportunities for drug discovery.
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2015 nî lūn-bûn
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2015年の論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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name
Structures of G protein-coupled receptors reveal new opportunities for drug discovery.
@en
type
label
Structures of G protein-coupled receptors reveal new opportunities for drug discovery.
@en
prefLabel
Structures of G protein-coupled receptors reveal new opportunities for drug discovery.
@en
P2093
P1433
P1476
Structures of G protein-coupled receptors reveal new opportunities for drug discovery
@en
P2093
Alastair J H Brown
Jonathan S Mason
Robert M Cooke
P304
P356
10.1016/J.DRUDIS.2015.08.003
P577
2015-08-22T00:00:00Z