Binding of complement factor H to endothelial cells is mediated by the carboxy-terminal glycosaminoglycan binding site.
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Structure of complement factor H carboxyl-terminus reveals molecular basis of atypical haemolytic uremic syndrome.Structural basis for engagement by complement factor H of C3b on a self surfaceDual interaction of factor H with C3d and glycosaminoglycans in host-nonhost discrimination by complementStructure of the N-terminal region of complement factor H and conformational implications of disease-linked sequence variationsGenetics of HUS: the impact of MCP, CFH, and IF mutations on clinical presentation, response to treatment, and outcomeStructure shows that a glycosaminoglycan and protein recognition site in factor H is perturbed by age-related macular degeneration-linked single nucleotide polymorphismProperdin: a tightly regulated critical inflammatory modulatorDisease-associated sequence variations congregate in a polyanion recognition patch on human factor H revealed in three-dimensional structureThe binding of factor H to a complex of physiological polyanions and C3b on cells is impaired in atypical hemolytic uremic syndrome.Leptospira interrogans endostatin-like outer membrane proteins bind host fibronectin, laminin and regulators of complementComplement in glomerular injury.What's new in haemolytic uraemic syndrome?Advances in understanding of pathogenesis of aHUS and HELLP.Mutations of factor H impair regulation of surface-bound C3b by three mechanisms in atypical hemolytic uremic syndrome.Atypical hemolytic uremic syndrome associated with complement factor H autoantibodies and CFHR1/CFHR3 deficiency.Genetics and complement in atypical HUS.Disease-associated N-terminal complement factor H mutations perturb cofactor and decay-accelerating activities.Red blood cell Thomsen-Friedenreich antigen expression and galectin-3 plasma concentrations in Streptococcus pneumoniae-associated hemolytic uremic syndrome and hemolytic anemia.Self-nonself discrimination by the complement system.HUS and atypical HUS.Staphylococcus aureus SdrE captures complement factor H's C-terminus via a novel 'close, dock, lock and latch' mechanism for complement evasionReview: Complement and its regulatory proteins in kidney diseases.Comparative proteomic analysis of serum from patients with systemic sclerosis and sclerodermatous GVHD. Evidence of defective function of factor HProperdin has an ascendancy over factor H regulation in complement-mediated renal tubular damage.Complement factor H-related proteins CFHR2 and CFHR5 represent novel ligands for the infection-associated CRASP proteins of Borrelia burgdorferi.Complement control protein factor H: the good, the bad, and the inadequate.Microbes bind complement inhibitor factor H via a common siteMolecular characterization of the interaction between sialylated Neisseria gonorrhoeae and factor H.Factor H mediated cell surface protection from complement is critical for the survival of PNH erythrocytes.Survey of the year 2005 commercial optical biosensor literature.Insights into the Effects of Complement Factor H on the Assembly and Decay of the Alternative Pathway C3 Proconvertase and C3 Convertase.Progress in defining the molecular biology of age related macular degeneration.Lyme borreliosis spirochete Erp proteins, their known host ligands, and potential roles in mammalian infection.Translational mini-review series on complement factor H: structural and functional correlations for factor H.Decidual endothelial cells express surface-bound C1q as a molecular bridge between endovascular trophoblast and decidual endothelium.The C-terminus of complement factor H is essential for host cell protection.Factor H and neisserial pathogenesis.A novel targeted inhibitor of the alternative pathway of complement and its therapeutic application in ischemia/reperfusion injury.Dynamic control of the complement system by modulated expression of regulatory proteins.Factor h: a complement regulator in health and disease, and a mediator of cellular interactions.
P2860
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P2860
Binding of complement factor H to endothelial cells is mediated by the carboxy-terminal glycosaminoglycan binding site.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Binding of complement factor H ...... lycosaminoglycan binding site.
@en
type
label
Binding of complement factor H ...... lycosaminoglycan binding site.
@en
prefLabel
Binding of complement factor H ...... lycosaminoglycan binding site.
@en
P2093
P2860
P50
P1476
Binding of complement factor H ...... lycosaminoglycan binding site.
@en
P2093
David L Gordon
Harald Seeberger
Jens Hellwage
Marina Noris
Mihály Jòzsi
Rebecca Ormsby
Seppo Meri
T Sakari Jokiranta
Zhu-Zhu Cheng
P2860
P304
P356
10.1016/S0002-9440(10)61205-9
P407
P577
2005-10-01T00:00:00Z