Biophysical Screening of a Focused Library for the Discovery of CYP121 Inhibitors as Novel Antimycobacterials.

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Biophysical Screening of a Focused Library for the Discovery of CYP121 Inhibitors as Novel Antimycobacterials.

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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2017年學術文章

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name

Biophysical Screening of a Foc ...... s as Novel Antimycobacterials.

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label

Biophysical Screening of a Foc ...... s as Novel Antimycobacterials.

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prefLabel

Biophysical Screening of a Foc ...... s as Novel Antimycobacterials.

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P1476

Biophysical Screening of a Foc ...... rs as Novel Antimycobacterials

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P2093

Ahmed A M Kamal

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Alexander Schifrin

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Andreas Thomann

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Christian Brengel

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Giuseppe Allegretta

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Isabell Schnorr

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Jens Eberhard

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Jörg Haupenthal

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Rolf W Hartmann

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Sang Hyun Cho

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P2860

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

Imidazole antibiotics inhibit the nitric oxide dioxygenase function of microbial flavohemoglobin.

Atomic structure of Mycobacterium tuberculosis CYP121 to 1.06 A reveals novel features of cytochrome P450

Characterization of Active Site Structure in CYP121: A CYTOCHROME P450 ESSENTIAL FOR VIABILITY OF MYCOBACTERIUM TUBERCULOSIS H37Rv

Identification and structural basis of the reaction catalyzed by CYP121, an essential cytochrome P450 in Mycobacterium tuberculosis

Structural and thermodynamic characterization of the adrenodoxin-like domain of the electron-transfer protein Etp1 from Schizosaccharomyces pombe

Substrate and Reaction Specificity of Mycobacterium tuberculosis Cytochrome P450 CYP121: INSIGHTS FROM BIOCHEMICAL STUDIES AND CRYSTAL STRUCTURES

Application of fragment screening and merging to the discovery of inhibitors of the Mycobacterium tuberculosis cytochrome P450 CYP121

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

Expression, purification and spectroscopic characterization of the cytochrome P450 CYP121 from Mycobacterium tuberculosis

P304

1616-1626

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P31

scholarly article

P356

10.1002/CMDC.201700363

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P433

http://www.w3.org/2001/XMLSchema#string

P478

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P50

Martin Empting

P577

2017-09-26T00:00:00Z

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P698

28815923

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