Intrinsic BET inhibitor resistance in SPOP-mutated prostate cancer is mediated by BET protein stabilization and AKT-mTORC1 activation.
about
SPOP-mediated degradation of BRD4 dictates cellular sensitivity to BET inhibitors.Recent Advances in Prostate Cancer Treatment and Drug Discovery.Epigenetic Regulation in Prostate Cancer Progression.Bromodomain protein BRD4 inhibitor JQ1 regulates potential prognostic molecules in advanced renal cell carcinoma.Dual inhibition of AKT-mTOR and AR signaling by targeting HDAC3 in PTEN- or SPOP-mutated prostate cancer.SPOP promotes ATF2 ubiquitination and degradation to suppress prostate cancer progression.Genetics and biology of prostate cancerRecent advances in prostate cancer research: large-scale genomic analyses reveal novel driver mutations and DNA repair defectsFunctional roles of Speckle-Type Poz (SPOP) Protein in Genomic stabilityUbiquitin Regulation: The Histone Modifying Enzyme's StoryFBP1 loss contributes to BET inhibitors resistance by undermining c-Myc expression in pancreatic ductal adenocarcinoma
P2860
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P2860
Intrinsic BET inhibitor resistance in SPOP-mutated prostate cancer is mediated by BET protein stabilization and AKT-mTORC1 activation.
description
2017 nî lūn-bûn
@nan
2017年の論文
@ja
2017年論文
@yue
2017年論文
@zh-hant
2017年論文
@zh-hk
2017年論文
@zh-mo
2017年論文
@zh-tw
2017年论文
@wuu
2017年论文
@zh
2017年论文
@zh-cn
name
Intrinsic BET inhibitor resist ...... ion and AKT-mTORC1 activation.
@en
type
label
Intrinsic BET inhibitor resist ...... ion and AKT-mTORC1 activation.
@en
prefLabel
Intrinsic BET inhibitor resist ...... ion and AKT-mTORC1 activation.
@en
P2093
P2860
P356
P1433
P1476
Intrinsic BET inhibitor resist ...... tion and AKT-mTORC1 activation
@en
P2093
Chenji Wang
Chun-Wu Pan
Dejie Wang
Haojie Huang
P2860
P2888
P304
P356
10.1038/NM.4379
P407
P50
P577
2017-08-14T00:00:00Z