The quorum-sensing molecule farnesol is a modulator of drug efflux mediated by ABC multidrug transporters and synergizes with drugs in Candida albicans.
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The ABCs of Candida albicans Multidrug Transporter Cdr1Mechanisms of Candida biofilm drug resistanceSynergistic combinations of antifungals and anti-virulence agents to fight against Candida albicansFarnesol-induced apoptosis in Candida albicans is mediated by Cdr1-p extrusion and depletion of intracellular glutathione.The metacaspase (Mca1p) has a dual role in farnesol-induced apoptosis in Candida albicans.FK520 interacts with the discrete intrahelical amino acids of multidrug transporter Cdr1 protein and acts as antagonist to selectively chemosensitize azole-resistant clinical isolates of Candida albicans.In vitro interactions between farnesol and fluconazole, amphotericin B or micafungin against Candida albicans biofilms.Detection of inhibitors of Candida albicans Cdr transporters using a diS-C3(3) fluorescence.From Biology to Drug Development: New Approaches to Combat the Threat of Fungal BiofilmsRationally designed transmembrane peptide mimics of the multidrug transporter protein Cdr1 act as antagonists to selectively block drug efflux and chemosensitize azole-resistant clinical isolates of Candida albicans.Reduced ABCB1 Expression and Activity in the Presence of Acrylic Copolymers.Quorum sensing in fungi--a review.Miconazole, a pharmacological barrier to skin fungal infections.Future directions for anti-biofilm therapeutics targeting Candida.Learning the ABC of oral fungal drug resistance.Candida Efflux ATPases and Antiporters in Clinical Drug Resistance.Fungal quorum sensing molecules: Role in fungal morphogenesis and pathogenicity.Targeting efflux pumps to overcome antifungal drug resistance.Synthetic Organotellurium Compounds Sensitize Drug-Resistant Candida albicans Clinical Isolates to Fluconazole.The in vitro and in vivo efficacy of fluconazole in combination with farnesol against Candida albicans isolates using a murine vulvovaginitis model.Farnesol signalling in Candida albicans - more than just communication.Farnesol inhibits translation to limit growth and filamentation in C. albicans and S. cerevisiae.Role of Mitochondrial Retrograde Pathway in Regulating Ethanol-Inducible Filamentous Growth in Yeast.Insight into pleiotropic drug resistance ATP-binding cassette pump drug transport through mutagenesis of Cdr1p transmembrane domains.The impact of farnesol in combination with fluconazole on Candida albicans biofilm: regulation of ERG20, ERG9, and ERG11 genes.Fungal Biofilms and Polymicrobial Diseases.Farnesol increases the susceptibility of Burkholderia pseudomallei biofilm to antimicrobials used to treat melioidosis.Microbial interactions within the plant holobiont.Nanotechnology-based drug delivery systems for control of microbial biofilms: a review.Dermatophyte Resistance to Antifungal Drugs: Mechanisms and Prospectus.Fungicidal action of geraniol against Candida albicans is potentiated by abrogated CaCdr1p drug efflux and fluconazole synergism
P2860
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P2860
The quorum-sensing molecule farnesol is a modulator of drug efflux mediated by ABC multidrug transporters and synergizes with drugs in Candida albicans.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
The quorum-sensing molecule fa ...... ith drugs in Candida albicans.
@en
type
label
The quorum-sensing molecule fa ...... ith drugs in Candida albicans.
@en
prefLabel
The quorum-sensing molecule fa ...... ith drugs in Candida albicans.
@en
P2860
P356
P1476
The quorum-sensing molecule fa ...... ith drugs in Candida albicans.
@en
P2093
Monika Sharma
Rajendra Prasad
P2860
P304
P356
10.1128/AAC.00344-11
P407
P577
2011-07-18T00:00:00Z