Therapeutics: Gene Therapy for Alpha-1 Antitrypsin Deficiency.

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Alpha-1 antitrypsin deficiency: outstanding questions and future directions.

P2860

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P2860

Therapeutics: Gene Therapy for Alpha-1 Antitrypsin Deficiency.

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

@zh-cn

2017年学术文章

@zh-hans

2017年学术文章

@zh-my

2017年学术文章

@zh-sg

2017年學術文章

@yue

2017年學術文章

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2017年學術文章

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name

Therapeutics: Gene Therapy for Alpha-1 Antitrypsin Deficiency.

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Item

label

Therapeutics: Gene Therapy for Alpha-1 Antitrypsin Deficiency.

@en

prefLabel

Therapeutics: Gene Therapy for Alpha-1 Antitrypsin Deficiency.

@en

P1476

Therapeutics: Gene Therapy for Alpha-1 Antitrypsin Deficiency.

@en

P2093

Alisha M Gruntman

http://www.w3.org/2001/XMLSchema#string

Terence R Flotte

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P2860

Neutrophil accumulation in the lung in alpha 1-antitrypsin deficiency. Spontaneous release of leukotriene B4 by alveolar macrophages

Mutation of antitrypsin to antithrombin. alpha 1-antitrypsin Pittsburgh (358 Met leads to Arg), a fatal bleeding disorder.

Expression of the human cystic fibrosis transmembrane conductance regulator gene in the mouse lung after in vivo intratracheal plasmid-mediated gene transfer.

Phase 2 clinical trial of a recombinant adeno-associated viral vector expressing α1-antitrypsin: interim results.

alpha-1 antitrypsin inhibits caspase-3 activity, preventing lung endothelial cell apoptosis.

Diversity of airway epithelial cell targets for in vivo recombinant adenovirus-mediated gene transfer.

Effect of cigarette smoke exposure and structural modifications on the α-1 Antitrypsin interaction with caspases.

Potential mechanism of emphysema: alpha 1-proteinase inhibitor recovered from lungs of cigarette smokers contains oxidized methionine and has decreased elastase inhibitory capacity.

Oxidative stress contributes to liver damage in a murine model of alpha-1-antitrypsin deficiency.

Sustained secretion of human alpha-1-antitrypsin from murine muscle transduced with adeno-associated virus vectors

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267-275

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scholarly article

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10.1007/978-1-4939-7163-3_27

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English

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1639

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P577

2017-01-01T00:00:00Z

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P698

28752467

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P921

gene therapy

Therapeutics: Gene Therapy for Alpha-1 Antitrypsin Deficiency.

about

P2860

P2860

Therapeutics: Gene Therapy for Alpha-1 Antitrypsin Deficiency.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P478

P577

P698

P921

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P478

P577

P698

P921