about
Impact of lysosome status on extracellular vesicle content and releaseGaps in Aging Research as it Applies to Rheumatologic Clinical Care.E3 Ubiquitin Ligases Neurobiological Mechanisms: Development to DegenerationImmune and myodegenerative pathomechanisms in inclusion body myositisDifferential adiponectin signalling couples ER stress with lipid metabolism to modulate ageing in C. elegansProtein homeostasis of a metastable subproteome associated with Alzheimer's disease.The endocytic pathway in microglia during health, aging and Alzheimer's disease.Stably Expressed Genes Involved in Basic Cellular Functions.Waterpipe smoking induces epigenetic changes in the small airway epithelium.Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice.Parkinson disease-linked GBA mutation effects reversed by molecular chaperones in human cell and fly models.Happily (n)ever after: Aging in the context of oxidative stress, proteostasis loss and cellular senescence.A Homeostatic Shift Facilitates Endoplasmic Reticulum Proteostasis through Transcriptional Integration of Proteostatic Stress Response Pathways.ER stress and the unfolded protein response in neurodegeneration.Super-multiplex vibrational imaging.The mitochondrial metabolic checkpoint and aging of hematopoietic stem cells.Modulation of Molecular Chaperones in Huntington's Disease and Other Polyglutamine Disorders.Cellular Regulation of Amyloid Formation in Aging and Disease.Non-enzymatic molecular damage as a prototypic driver of aging.Shaping proteostasis at the cellular, tissue, and organismal level.Endoplasmic reticulum proteostasis impairment in agingAutophagy in the presynaptic compartment in health and disease.Regulating Secretory Proteostasis through the Unfolded Protein Response: From Function to Therapy.Repair or destruction-an intimate liaison between ubiquitin ligases and molecular chaperones in proteostasisAutophagy in neurodegenerative diseases: pathogenesis and therapy.Epithelial cell senescence: an adaptive response to pre-carcinogenic stresses?UVB-Induced Senescence of Human Dermal Fibroblasts Involves Impairment of Proteasome and Enhanced Autophagic Activity.ER Stress and Neurodegenerative Disease: A Cause or Effect Relationship?IRE1 signaling exacerbates Alzheimer's disease pathogenesis.Commentary: Life course epidemiology embraces geroscience.Commentary: XBP-1 Is a Cell-Nonautonomous Regulator of Stress Resistance and Longevity.Role of Dendritic Cells in Inflammation and Loss of Tolerance in the Elderly.AKT2 suppresses pro-survival autophagy triggered by DNA double-strand breaks in colorectal cancer cells.Chaperone-directed ubiquitylation maintains proteostasis at the expense of longevity.Inflammaging and the Lung.Role of nerve-muscle interactions and reactive oxygen species in regulation of muscle proteostasis with ageing.Age-associated dysregulation of protein metabolism in the mammalian oocyte.Hyperactivation of the Insulin Signaling Pathway Improves Intracellular Proteostasis by Coordinately Up-regulating the Proteostatic Machinery in Adipocytes.Molecular Age-Related Changes in the Anterior Segment of the Eye.Emerging roles of ER stress in the etiology and pathogenesis of Alzheimer's disease.
P2860
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P2860
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
@zh
2015年學術文章
@zh-hant
name
Proteostasis and aging.
@en
type
label
Proteostasis and aging.
@en
prefLabel
Proteostasis and aging.
@en
P2860
P356
P1433
P1476
Proteostasis and aging.
@en
P2093
Susmita Kaushik
P2860
P2888
P304
P356
10.1038/NM.4001
P407
P577
2015-12-01T00:00:00Z
P6179
1033876263