Nature of protective immunity to Francisella tularensis.
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TularemiaGalleria mellonella as a model host to study infection by the Francisella tularensis live vaccine strainThe involvement of IL-17A in the murine response to sub-lethal inhalational infection with Francisella tularensisSignatures of T cells as correlates of immunity to Francisella tularensisImmunoproteomics analysis of the murine antibody response to vaccination with an improved Francisella tularensis live vaccine strain (LVS)Live attenuated tularemia vaccines: recent developments and future goals.Single-Stranded DNA Aptamers against Pathogens and Toxins: Identification and Biosensing Applications.Live attenuated mutants of Francisella tularensis protect rabbits against aerosol challenge with a virulent type A strain.Role of TLR signaling in Francisella tularensis-LPS-induced, antibody-mediated protection against Francisella tularensis challenge.Rapid dissemination of Francisella tularensis and the effect of route of infection.Novel modification of lipid A of Francisella tularensisGenome sequencing shows that European isolates of Francisella tularensis subspecies tularensis are almost identical to US laboratory strain Schu S4.Inhibition of expression in Escherichia coli of a virulence regulator MglB of Francisella tularensis using external guide sequence technology.Glutathione provides a source of cysteine essential for intracellular multiplication of Francisella tularensis.The Fischer 344 rat reflects human susceptibility to francisella pulmonary challenge and provides a new platform for virulence and protection studiesGallium disrupts iron uptake by intracellular and extracellular Francisella strains and exhibits therapeutic efficacy in a murine pulmonary infection model.Phagosomal retention of Francisella tularensis results in TIRAP/Mal-independent TLR2 signaling.The type IV pilin, PilA, is required for full virulence of Francisella tularensis subspecies tularensis.A tolC mutant of Francisella tularensis is hypercytotoxic compared to the wild type and elicits increased proinflammatory responses from host cells.Molecular immune responses to aerosol challenge with Francisella tularensis in mice inoculated with live vaccine candidates of varying efficacy.Detoxified endotoxin vaccine (J5dLPS/OMP) protects mice against lethal respiratory challenge with Francisella tularensis SchuS4.Intranasal vaccination induces protective immunity against intranasal infection with virulent Francisella tularensis biovar AStructure and function relations with a T-cell-activating polysaccharide antigen using circular dichroism.Rapid local expression of interleukin-12, tumor necrosis factor alpha, and gamma interferon after cutaneous Francisella tularensis infection in tularemia-immune mice.Importance of B cells, but not specific antibodies, in primary and secondary protective immunity to the intracellular bacterium Francisella tularensis live vaccine strainPurified lipopolysaccharide from Francisella tularensis live vaccine strain (LVS) induces protective immunity against LVS infection that requires B cells and gamma interferon.Long lived protection against pneumonic tularemia is correlated with cellular immunity in peripheral, not pulmonary, organs.Development of functional and molecular correlates of vaccine-induced protection for a model intracellular pathogen, F. tularensis LVS.Construction of a bioluminescence reporter plasmid for Francisella tularensisTularemia from domestic catsDotU and VgrG, core components of type VI secretion systems, are essential for Francisella LVS pathogenicityInternalization and phagosome escape required for Francisella to induce human monocyte IL-1beta processing and releaseImmune responses in macaques to a prototype recombinant adenovirus live oral human papillomavirus 16 vaccine.Cellular and humoral immunity are synergistic in protection against types A and B Francisella tularensis.Unique substrates secreted by the type VI secretion system of Francisella tularensis during intramacrophage infection.Intranasal vaccination with a defined attenuated Francisella novicida strain induces gamma interferon-dependent antibody-mediated protection against tularemia.T-cell-independent resistance to infection and generation of immunity to Francisella tularensis.Neutrophils are critical for host defense against primary infection with the facultative intracellular bacterium Francisella tularensis in mice and participate in defense against reinfectionTransfer of immunity against lethal murine Francisella infection by specific antibody depends on host gamma interferon and T cells.Mouse models of aerosol-acquired tularemia caused by Francisella tularensis types A and B.
P2860
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P2860
Nature of protective immunity to Francisella tularensis.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年学术文章
@wuu
1989年学术文章
@zh-cn
1989年学术文章
@zh-hans
1989年学术文章
@zh-my
1989年学术文章
@zh-sg
1989年學術文章
@yue
1989年學術文章
@zh
1989年學術文章
@zh-hant
name
Nature of protective immunity to Francisella tularensis.
@en
type
label
Nature of protective immunity to Francisella tularensis.
@en
prefLabel
Nature of protective immunity to Francisella tularensis.
@en
P1476
Nature of protective immunity to Francisella tularensis
@en
P2093
P304
P577
1989-05-01T00:00:00Z