A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease.
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Microglia Responses in Acute and Chronic Neurological Diseases: What Microglia-Specific Transcriptomic Studies Taught (and did Not Teach) Us.TREM2 in Neurodegenerative Diseases.Novel Influences of IL-10 on CNS Inflammation Revealed by Integrated Analyses of Cytokine Networks and Microglial Morphology.TREM2 shedding by cleavage at the H157-S158 bond is accelerated for the Alzheimer's disease-associated H157Y variant.Temporal Tracking of Microglia Activation in Neurodegeneration at Single-Cell Resolution.Single-cell transcriptomics to explore the immune system in health and disease.TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy.In Vivo Imaging of Microglial Calcium Signaling in Brain Inflammation and Injury.The immunogenetics of neurological disease.Microglia and macrophages in brain homeostasis and disease.Microglia-Mediated Neuroprotection, TREM2, and Alzheimer's Disease: Evidence From Optical Imaging.Splitting the "Unsplittable": Dissecting Resident and Infiltrating Macrophages in Experimental Autoimmune Encephalomyelitis.Lysophosphatidic acid via LPA-receptor 5/protein kinase D-dependent pathways induces a motile and pro-inflammatory microglial phenotype.Phagocytic Roles of Glial Cells in Healthy and Diseased Brains.Alzheimer's Disease: The Role of Microglia in Brain Homeostasis and Proteopathy.Activation of the STING-Dependent Type I Interferon Response Reduces Microglial Reactivity and Neuroinflammation.Erythromyeloid-Derived TREM2: A Major Determinant of Alzheimer's Disease Pathology in Down Syndrome.The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases.Microglia emerge as central players in brain disease.Microglia Gone Rogue: Impacts on Psychiatric Disorders across the Lifespan.Tissue-Resident Macrophages in Fungal Infections.Microglial interactions with the neurovascular system in physiology and pathology.RIPK1 mediates a disease-associated microglial response in Alzheimer's disease.Functional and structural damage of neurons by innate immune mechanisms during neurodegeneration.Innate immune alterations are elicited in microglial cells before plaque deposition in the Alzheimer's disease mouse model 5xFAD.Reactive Astrocytes in Brain Metastasis.Neuroimmunology in 2017: The central nervous system: privileged by immune connections.Autophagy gene FIP200 in neural progenitors non-cell autonomously controls differentiation by regulating microglia.The promise of spatial transcriptomics for neuroscience in the era of molecular cell typing.The Role of Microglia and Macrophages in CNS Homeostasis, Autoimmunity, and Cancer.Differential contribution of microglia and monocytes in neurodegenerative diseases.Spatial reconstruction of immune niches by combining photoactivatable reporters and scRNA-seq.Can immunotherapy treat neurodegeneration?Humanized TREM2 mice reveal microglia-intrinsic and -extrinsic effects of R47H polymorphism.Deciphering microglial diversity in Alzheimer's disease.RIPK1 promotes inflammation and β-amyloid accumulation in Alzheimer's disease.Microglia-mediated recovery from ALS-relevant motor neuron degeneration in a mouse model of TDP-43 proteinopathy.Neuroinflammation: Microglia and T Cells Get Ready to Tango.A genetically distinct microglial subset promotes myelination.Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer's Disease Models.
P2860
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P2860
A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease.
description
2017 nî lūn-bûn
@nan
2017年の論文
@ja
2017年論文
@yue
2017年論文
@zh-hant
2017年論文
@zh-hk
2017年論文
@zh-mo
2017年論文
@zh-tw
2017年论文
@wuu
2017年论文
@zh
2017年论文
@zh-cn
name
A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease.
@en
type
label
A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease.
@en
prefLabel
A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease.
@en
P2093
P921
P1433
P1476
A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease.
@en
P2093
Amit Spinrad
Assaf Weiner
Beata Toth
David Lara-Astaiso
Eyal David
Hadas Keren-Shaul
Kuti Baruch
Marco Colonna
Michal Schwartz
P304
1276-1290.e17
P356
10.1016/J.CELL.2017.05.018
P407
P577
2017-06-07T00:00:00Z