Differential requirement of SUFU in tissue development discovered in a hypomorphic mouse model.

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Differential requirement of SUFU in tissue development discovered in a hypomorphic mouse model.

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2017 nî lūn-bûn

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Differential requirement of SU ...... in a hypomorphic mouse model.

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Differential requirement of SU ...... in a hypomorphic mouse model.

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Differential requirement of SU ...... in a hypomorphic mouse model.

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P1476

Differential requirement of SU ...... in a hypomorphic mouse model.

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P2093

Cornelius Trünkle

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José M Dias

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Karin Heby-Henricson

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Maria A Hoelzl

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Rune Toftgård

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Stephan Teglund

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Åsa Bergström

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P2860

Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3

Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-1

Characterization of the human suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli

Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro

Suppressor of Fused represses Gli-mediated transcription by recruiting the SAP18-mSin3 corepressor complex

Suppressor of fused regulates Gli activity through a dual binding mechanism

Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation

The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins

Mutations in the human Sonic Hedgehog gene cause holoprosencephaly

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132-146

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scholarly article

P356

10.1016/J.YDBIO.2017.06.037

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English

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P478

429

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P50

Raoul Kuiper

Johan Ericson

Marco Gerling

P577

2017-07-05T00:00:00Z

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P698

28688895

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P932

5569906

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