Basal hypersecretion of glucagon and insulin from palmitate-exposed human islets depends on FFAR1 but not decreased somatostatin secretion

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20-HETE promotes glucose-stimulated insulin secretion in an autocrine manner through FFAR1.Dissecting the Physiology and Pathophysiology of Glucagon-Like Peptide-1

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Basal hypersecretion of glucagon and insulin from palmitate-exposed human islets depends on FFAR1 but not decreased somatostatin secretion

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Basal hypersecretion of glucag ...... creased somatostatin secretion

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Basal hypersecretion of glucag ...... creased somatostatin secretion

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Basal hypersecretion of glucag ...... creased somatostatin secretion

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P1476

Basal hypersecretion of glucag ...... creased somatostatin secretion

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D M Smith

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E Sargsyan

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H Kristinsson

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H Manell

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P Bergsten

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S O Göpel

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P2860

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40.

Oleic acid interacts with GPR40 to induce Ca2+ signaling in rat islet beta-cells: mediation by PLC and L-type Ca2+ channel and link to insulin release.

G-protein-coupled receptor 40 (GPR40) expression and its regulation in human pancreatic islets: the role of type 2 diabetes and fatty acids.

Glucagon and plasma catecholamine responses to graded and prolonged exercise in man.

Muscarinic stimulation of pancreatic insulin and glucagon release is abolished in m3 muscarinic acetylcholine receptor-deficient mice.

Identification and pharmacological characterization of multiple allosteric binding sites on the free fatty acid 1 receptor

Alpha-cells of the endocrine pancreas: 35 years of research but the enigma remains.

The role of alpha-cell dysregulation in fasting and postprandial hyperglycemia in type 2 diabetes and therapeutic implications.

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s41598-017-04730-5

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scholarly article

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10.1038/S41598-017-04730-5

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English

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2017-07-05T00:00:00Z

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Basal hypersecretion of glucagon and insulin from palmitate-exposed human islets depends on FFAR1 but not decreased somatostatin secretion

about

P2860

P2860

Basal hypersecretion of glucagon and insulin from palmitate-exposed human islets depends on FFAR1 but not decreased somatostatin secretion

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P407

P433

P478

P577

P6179

P698

P932

P356

P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P407

P433

P478

P577

P6179

P698

P932