Protein misfolding in the endoplasmic reticulum as a conduit to human disease.
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Targeting p97 to Disrupt Protein Homeostasis in CancerAdaptive preconditioning in neurological diseases – therapeutic insights from proteostatic perturbationsAxon injury induced endoplasmic reticulum stress and neurodegenerationThe unfolded protein response in immunity and inflammationRNA binding motif protein 3: a potential biomarker in cancer and therapeutic target in neuroprotection.Role of activating transcription factor 4 in the hepatic response to amino acid depletion by asparaginase.Endoplasmic reticulum stress and inflammation in the central nervous systemEndoplasmic Reticulum Stress Caused by Lipoprotein Accumulation Suppresses Immunity against Bacterial Pathogens and Contributes to ImmunosenescenceA novel potential biomarker for metabolic syndrome in Chinese adults: Circulating protein disulfide isomerase family A, member 4.Plasminogen Tochigi mice exhibit phenotypes similar to wild-type mice under experimental thrombotic conditions.Spoxazomicin D and Oxachelin C, Potent Neuroprotective Carboxamides from the Appalachian Coal Fire-Associated Isolate Streptomyces sp. RM-14-6.Stably Expressed Genes Involved in Basic Cellular Functions.Mutant uromodulin expression leads to altered homeostasis of the endoplasmic reticulum and activates the unfolded protein response.General control nonderepressible 2 deletion predisposes to asparaginase-associated pancreatitis in mice.Vitamin E δ-tocotrienol triggers endoplasmic reticulum stress-mediated apoptosis in human melanoma cells.Lipid disequilibrium disrupts ER proteostasis by impairing ERAD substrate glycan trimming and dislocation.Achromatopsia mutations target sequential steps of ATF6 activation.Adiponectin reduces ER stress-induced apoptosis through PPARα transcriptional regulation of ATF2 in mouse adiposeProstate cancer and the unfolded protein response.Exosomes derived from human platelet-rich plasma prevent apoptosis induced by glucocorticoid-associated endoplasmic reticulum stress in rat osteonecrosis of the femoral head via the Akt/Bad/Bcl-2 signal pathway.Endoplasmic reticulum stress, a new wrestler, in the pathogenesis of idiopathic pulmonary fibrosis.A Homeostatic Shift Facilitates Endoplasmic Reticulum Proteostasis through Transcriptional Integration of Proteostatic Stress Response Pathways.Human protein secretory pathway genes are expressed in a tissue-specific pattern to match processing demands of the secretome.ER stress and the unfolded protein response in neurodegeneration.GRP78 at the Centre of the Stage in Cancer and Neuroprotection.Formaldehyde Is a Potent Proteotoxic Stressor Causing Rapid Heat Shock Transcription Factor 1 Activation and Lys48-Linked Polyubiquitination of Proteins.Peroxisome Proliferator-activated Receptor-γ Activation Augments the β-Cell Unfolded Protein Response and Rescues Early Glycemic Deterioration and β Cell Death in Non-obese Diabetic MiceModulation of Molecular Chaperones in Huntington's Disease and Other Polyglutamine Disorders.Endoplasmic reticulum stress in human photoreceptor diseases.Toxicogenomic module associations with pathogenesis: a network-based approach to understanding drug toxicity.The role of ER stress in lipid metabolism and lipotoxicity.Guided folding takes a start from the molecular imprinting of structured epitopes.Anticipatory UPR Activation: A Protective Pathway and Target in Cancer.Guanylyl Cyclase C Hormone Axis at the Intersection of Obesity and Colorectal Cancer.p62/SQSTM1-Dr. Jekyll and Mr. Hyde that prevents oxidative stress but promotes liver cancer.The integrated stress response.NF-Y (CBF) regulation in specific cell types and mouse models.When proteostasis goes bad: Protein aggregation in the cell.Endoplasmic Reticulum Protein Quality Control Failure in Myelin Disorders.Mechanisms of cell death induction by food-borne mycotoxins.
P2860
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P2860
Protein misfolding in the endoplasmic reticulum as a conduit to human disease.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年学术文章
@wuu
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
@zh
2016年學術文章
@zh-hant
name
Protein misfolding in the endoplasmic reticulum as a conduit to human disease.
@en
type
label
Protein misfolding in the endoplasmic reticulum as a conduit to human disease.
@en
prefLabel
Protein misfolding in the endoplasmic reticulum as a conduit to human disease.
@en
P2860
P356
P1433
P1476
Protein misfolding in the endoplasmic reticulum as a conduit to human disease.
@en
P2093
Randal J Kaufman
P2860
P2888
P304
P356
10.1038/NATURE17041
P407
P577
2016-01-01T00:00:00Z