Anti-leukaemic activity of the TYK2 selective inhibitor NDI-031301 in T-cell acute lymphoblastic leukaemia.

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B lymphoblastic leukemia/lymphoma: new insights into genetics, molecular aberrations, subclassification and targeted therapy.Targeted therapies for T-cell acute lymphoblastic leukaemia (T-ALL): what makes T-ALL TYK?

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Anti-leukaemic activity of the TYK2 selective inhibitor NDI-031301 in T-cell acute lymphoblastic leukaemia.

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http://www.wikidata.org/entity/Q38712212

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2017 nî lūn-bûn

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2017年の論文

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2017年論文

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2017年論文

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2017年論文

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2017年論文

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2017年論文

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2017年论文

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2017年论文

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name

Anti-leukaemic activity of the ...... acute lymphoblastic leukaemia.

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Anti-leukaemic activity of the ...... acute lymphoblastic leukaemia.

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Anti-leukaemic activity of the ...... acute lymphoblastic leukaemia.

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Anti-leukaemic activity of the ...... acute lymphoblastic leukaemia

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P2093

A Thomas Look

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Alla Berezovskaya

http://www.w3.org/2001/XMLSchema#string

Craig E Masse

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David M Weinstock

http://www.w3.org/2001/XMLSchema#string

Evisa Gjini

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Jennifer Rocnik

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Jeremy R Greenwood

http://www.w3.org/2001/XMLSchema#string

Julia Etchin

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Koshi Akahane

http://www.w3.org/2001/XMLSchema#string

Rosana Kapeller

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P2860

Janus kinases in immune cell signaling

Lead optimization of a 4-aminopyridine benzamide scaffold to identify potent, selective, and orally bioavailable TYK2 inhibitors

Lead identification of novel and selective TYK2 inhibitors

Human TYK2 deficiency: Mycobacterial and viral infections without hyper-IgE syndrome

Human tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunity

Jaks and STATs: biological implications

BCL2-specific inhibitor ABT-199 synergizes strongly with cytarabine against the early immature LOUCY cell line but not more-differentiated T-ALL cell lines.

Partial impairment of cytokine responses in Tyk2-deficient mice.

Tyk2 plays a restricted role in IFN alpha signaling, although it is required for IL-12-mediated T cell function.

Maturation stage of T-cell acute lymphoblastic leukemia determines BCL-2 versus BCL-XL dependence and sensitivity to ABT-199

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271-282

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scholarly article

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10.1111/BJH.14563

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English

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177

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Hong Tiv

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2017-03-14T00:00:00Z

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28295194

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leukemia

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5384871

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Anti-leukaemic activity of the TYK2 selective inhibitor NDI-031301 in T-cell acute lymphoblastic leukaemia.

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P2860

P2860

Anti-leukaemic activity of the TYK2 selective inhibitor NDI-031301 in T-cell acute lymphoblastic leukaemia.

description

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type

label

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P1433

P1476

P2093

P2860

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P356

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P433

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P50

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P1433

P1476

P2093

P2860

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P31

P356

P407

P433

P478

P50

P577

P698

P921

P932