Proteoglycans in the pathogenesis of Alzheimer's disease and other amyloidoses.
about
Perlecan maintains the integrity of cartilage and some basement membranesHeparan sulfate proteoglycan induces the production of NO and TNF-alpha by murine microglia.Heparan sulfate proteoglycans in experimental models of diabetes: a role for perlecan in diabetes complicationsCommon binding sites for beta-amyloid fibrils and fibroblast growth factor-2 in heparan sulfate from human cerebral cortexAgrin in Alzheimer's disease: altered solubility and abnormal distribution within microvasculature and brain parenchymaIdentification of a heparin binding domain in the N-terminal cleavage site of pro-islet amyloid polypeptide. Implications for islet amyloid formation.Amyloid arthropathy in chickens.Amyloid beta peptide: a century of discoveries.Heparin oligosaccharides as potential therapeutic agents in senile dementiaMetalloendoprotease cleavage triggers gelsolin amyloidogenesisAgrin is a major heparan sulfate proteoglycan accumulating in Alzheimer's disease brain.Early accumulation of heparan sulfate in neurons and in the beta-amyloid protein-containing lesions of Alzheimer's disease and Down's syndrome.Heparan sulfate proteoglycan in diffuse plaques of hippocampus but not of cerebellum in Alzheimer's disease brain.Amyloid accomplices and enforcersAmyloid formation in heterogeneous environments: islet amyloid polypeptide glycosaminoglycan interactionsAvian amyloidosis.A critical assessment of the role of helical intermediates in amyloid formation by natively unfolded proteins and polypeptides.Amnestic effects in mice of four synthetic peptides homologous to amyloid beta protein from patients with Alzheimer disease.Drugs to treat age-related neurodegenerative problems. The final frontier of medical science?The effect of glycosaminoglycans (GAGs) on amyloid aggregation and toxicity.The Alzheimer's disease risk factors apolipoprotein E and TREM2 are linked in a receptor signaling pathwayInhibition of glycosaminoglycan-mediated amyloid formation by islet amyloid polypeptide and proIAPP processing intermediates.Heparan Sulfate Proteoglycans Are Important for Islet Amyloid Formation and Islet Amyloid Polypeptide-induced Apoptosis.A role for helical intermediates in amyloid formation by natively unfolded polypeptides?Localization of perlecan (or a perlecan-related macromolecule) to isolated microglia in vitro and to microglia/macrophages following infusion of beta-amyloid protein into rodent hippocampus.Overproduction of perlecan core protein in cultured cells and transgenic mice.The ability of insulin to inhibit the formation of amyloid by pro-islet amyloid polypeptide processing intermediates is significantly reduced in the presence of sulfated glycosaminoglycans.Sulfated glycosaminoglycans in protein aggregation diseases.Sulfated glycans and elevated temperature stimulate PrP(Sc)-dependent cell-free formation of protease-resistant prion protein.The toxicity in vitro of beta-amyloid protein.Age-related fibrillar material in mouse brain. Assessing its potential as a biomarker of aging and as a model of human neurodegenerative disease.Scrapie-associated PrP accumulation and its inhibition: revisiting the amyloid-glycosaminoglycan connection.The presence of a novel protein in calf serum that recognizes beta amyloid in the formalin-fixed section.Isolation and characterization of the integral glycosaminoglycan constituents of human amyloid A and monoclonal light-chain amyloid fibrils.Structure of heparan sulphate from human brain, with special regard to Alzheimer's diseaseCharacterization of proteoglycans associated with mouse splenic AA amyloidosis.Differences in extracellular matrix production and basic fibroblast growth factor response in skin fibroblasts from sporadic and familial Alzheimer's disease.Overexpression of heparanase lowers the amyloid burden in amyloid-β precursor protein transgenic mice.Transthyretin-related vitreous amyloidosis in different endemic areas.Identification of iduronate-2-sulfatase in mouse pancreatic islets.
P2860
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P2860
Proteoglycans in the pathogenesis of Alzheimer's disease and other amyloidoses.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
Proteoglycans in the pathogenesis of Alzheimer's disease and other amyloidoses.
@en
type
label
Proteoglycans in the pathogenesis of Alzheimer's disease and other amyloidoses.
@en
prefLabel
Proteoglycans in the pathogenesis of Alzheimer's disease and other amyloidoses.
@en
P1476
Proteoglycans in the pathogenesis of Alzheimer's disease and other amyloidoses.
@en
P2093
P304
P356
10.1016/0197-4580(89)90108-5
P577
1989-09-01T00:00:00Z