Sulfated glycans and elevated temperature stimulate PrP(Sc)-dependent cell-free formation of protease-resistant prion protein.
about
Glypican-1 mediates both prion protein lipid raft association and disease isoform formationSelective incorporation of polyanionic molecules into hamster prions.Formation of native prions from minimal components in vitroCellular aspects of prion replication in vitroStructure of the Flexible Amino-Terminal Domain of Prion Protein Bound to a Sulfated GlycanA computational approach for identifying the chemical factors involved in the glycosaminoglycans-mediated acceleration of amyloid fibril formationIn situ photodegradation of incorporated polyanion does not alter prion infectivityCharge neutralization of the central lysine cluster in prion protein (PrP) promotes PrP(Sc)-like folding of recombinant PrP amyloids.Getting a grip on prions: oligomers, amyloids, and pathological membrane interactions.Production of cattle lacking prion protein.Prion protein self-peptides modulate prion interactions and conversion.The expanding universe of prion diseases.Fatal transmissible amyloid encephalopathy: a new type of prion disease associated with lack of prion protein membrane anchoringHeparin binding confers prion stability and impairs its aggregation.Glycosaminoglycan sulphation affects the seeded misfolding of a mutant prion proteinSulfated dextrans enhance in vitro amplification of bovine spongiform encephalopathy PrP(Sc) and enable ultrasensitive detection of bovine PrP(Sc).Low density subcellular fractions enhance disease-specific prion protein misfolding.Molecular interactions between prions as seeds and recombinant prion proteins as substrates resemble the biological interspecies barrier in vitroRedox control of prion and disease pathogenesis.Synthesis of high titer infectious prions with cofactor molecules.Heparin induces harmless fibril formation in amyloidogenic W7FW14F apomyoglobin and amyloid aggregation in wild-type protein in vitro.Biochemistry. What makes a prion infectious?The role of cofactors in prion propagation and infectivityLipopolysaccharide induced conversion of recombinant prion protein.Species-dependent differences in cofactor utilization for formation of the protease-resistant prion protein in vitro.Potent antiscrapie activities of degenerate phosphorothioate oligonucleotides.Glycosylphosphatidylinositol anchor-dependent stimulation pathway required for generation of baculovirus-derived recombinant scrapie prion protein.Prion protein misfolding.Prion strain-dependent differences in conversion of mutant prion proteins in cell culture.In vitro detection of prionemia in TSE-infected cervids and hamsters.Insect cell-derived cofactors become fully functional after proteinase K and heat treatment for high-fidelity amplification of glycosylphosphatidylinositol-anchored recombinant scrapie and BSE prion proteins.Amyloidogenesis: historical and modern observations point to heparan sulfate proteoglycans as a major culprit.Human prion proteins with pathogenic mutations share common conformational changes resulting in enhanced binding to glycosaminoglycansRecent advances in prion chemotherapeutics.Efficient in vitro amplification of chronic wasting disease PrPRES.Modulation of Glycosaminoglycans Affects PrPSc Metabolism but Does Not Block PrPSc Uptake.Early Generation of New PrPSc on Blood Vessels after Brain Microinjection of Scrapie in MiceIn vitro amplification of scrapie and chronic wasting disease PrP(res) using baculovirus-expressed recombinant PrP as substrateVolume and energy folding landscape of prion protein revealed by pressure.The role of the 132-160 region in prion protein conformational transitions.
P2860
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P2860
Sulfated glycans and elevated temperature stimulate PrP(Sc)-dependent cell-free formation of protease-resistant prion protein.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Sulfated glycans and elevated temperature stimulate PrP
@nl
Sulfated glycans and elevated ...... tease-resistant prion protein.
@en
type
label
Sulfated glycans and elevated temperature stimulate PrP
@nl
Sulfated glycans and elevated ...... tease-resistant prion protein.
@en
prefLabel
Sulfated glycans and elevated temperature stimulate PrP
@nl
Sulfated glycans and elevated ...... tease-resistant prion protein.
@en
P2093
P2860
P356
P1433
P1476
Sulfated glycans and elevated ...... tease-resistant prion protein.
@en
P2093
Chesebro B
Horiuchi M
P2860
P304
P356
10.1093/EMBOJ/20.3.377
P407
P577
2001-02-01T00:00:00Z