A new nitrobenzoxadiazole-based GSTP1-1 inhibitor with a previously unheard of mechanism of action and high stability.

about

6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio) hexanol: a promising new anticancer compound.Glutathione S -transferase π: a potential role in antitumor therapy

P2860

Q47718656-01B37593-9862-46F6-B220-4C66CE279D7A Q58694500-B067C0FB-45D2-4CBC-8117-E6F5C9A97F1D

P2860

A new nitrobenzoxadiazole-based GSTP1-1 inhibitor with a previously unheard of mechanism of action and high stability.

Item

http://www.wikidata.org/entity/Q38720837

description

2017 nî lūn-bûn

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2017年の論文

@ja

2017年論文

@yue

2017年論文

@zh-hant

2017年論文

@zh-hk

2017年論文

@zh-mo

2017年論文

@zh-tw

2017年论文

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2017年论文

@zh

2017年论文

@zh-cn

name

A new nitrobenzoxadiazole-base ...... of action and high stability.

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type

Item

label

A new nitrobenzoxadiazole-base ...... of action and high stability.

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prefLabel

A new nitrobenzoxadiazole-base ...... of action and high stability.

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P1476

A new nitrobenzoxadiazole-base ...... of action and high stability.

@en

P2093

Anna M Caccuri

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Antonello Mai

http://www.w3.org/2001/XMLSchema#string

Blasco Morozzo Della Rocca

http://www.w3.org/2001/XMLSchema#string

Chiara Fulci

http://www.w3.org/2001/XMLSchema#string

Dante Rotili

http://www.w3.org/2001/XMLSchema#string

Lorenzo Stella

http://www.w3.org/2001/XMLSchema#string

Mariantonietta Forgione

http://www.w3.org/2001/XMLSchema#string

Veronica Di Paolo

http://www.w3.org/2001/XMLSchema#string

P2860

Human glutathione S-transferase P1-1 interacts with TRAF2 and regulates TRAF2-ASK1 signals

The fine-tuning of TRAF2-GSTP1-1 interaction: effect of ligand binding and in situ detection of the complex

A novel orally active water-soluble inhibitor of human glutathione transferase exerts a potent and selective antitumor activity against human melanoma xenografts.

Glutathione transferases and development of new principles to overcome drug resistance.

Synthesis and structure--activity relationship of new cytotoxic agents targeting human glutathione-S-transferases.

New insights into the mechanism of JNK1 inhibition by glutathione transferase P1-1.

Targeting GSTP1-1 induces JNK activation and leads to apoptosis in cisplatin-sensitive and -resistant human osteosarcoma cell lines.

The glutathione transferase inhibitor 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) increases temozolomide efficacy against malignant melanoma.

In vitro and in vivo efficacy of 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) on human melanoma.

7-Nitro-2,1,3-benzoxadiazole derivatives, a new class of suicide inhibitors for glutathione S-transferases. Mechanism of action of potential anticancer drugs.

P304

240-247

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P31

scholarly article

P356

10.1080/14756366.2016.1247059

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Mattia Falconi

Anastasia De Luca

Luigi Quintieri

P577

2017-12-01T00:00:00Z

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P698

28097896

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P932

6009906

http://www.w3.org/2001/XMLSchema#string

A new nitrobenzoxadiazole-based GSTP1-1 inhibitor with a previously unheard of mechanism of action and high stability.

about

P2860

P2860

A new nitrobenzoxadiazole-based GSTP1-1 inhibitor with a previously unheard of mechanism of action and high stability.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P932