about
Binding to DPF-motif by the POB1 EH domain is responsible for POB1-Eps15 interactionThe fragile X syndrome protein represses activity-dependent translation through CYFIP1, a new 4E-BPThe relevance of piroxicam for the prevention and treatment of nonmelanoma skin cancer and its precursorsActive-site copper and zinc ions modulate the quaternary structure of prokaryotic Cu,Zn superoxide dismutaseThe Salmonella enterica ZinT structure, zinc affinity and interaction with the high-affinity uptake protein ZnuA provide insight into the management of periplasmic zincEvolutionary constraints for dimer formation in prokaryotic Cu,Zn superoxide dismutaseSuperefficient enzymesStructural dynamics of the mitochondrial ADP/ATP carrier revealed by molecular dynamics simulation studiesStructural and dynamic properties of the homodimeric hemoglobin from Scapharca inaequivalvis Thr-72-->Ile mutant: molecular dynamics simulation, low temperature visible absorption spectroscopy, and resonance Raman spectroscopy studies.Molecular dynamics of the DNA-binding domain of the papillomavirus E2 transcriptional regulator uncover differential properties for DNA target accommodation.Modelling the three-dimensional structure and electrostatic potential field of the two Cu,Zn superoxide dismutase variants from Xenopus laevis.Experimental and simulative dissociation of dimeric Cu,Zn superoxide dismutase doubly mutated at the intersubunit surfacePolymorphism in Mitochondrial Coding Regions of Mediterranean Loggerhead Turtles: Evolutionary Relevance and Structural Effects.Molecular dynamics simulation of human LOX-1 provides an explanation for the lack of OxLDL binding to the Trp150Ala mutant.MD simulations of papillomavirus DNA-E2 protein complexes hints at a protein structural code for DNA deformation.Role of the electrostatic loop of Cu,Zn superoxide dismutase in the copper uptake process.Functional analysis and molecular dynamics simulation of LOX-1 K167N polymorphism reveal alteration of receptor activity.BC1-FMRP interaction is modulated by 2'-O-methylation: RNA-binding activity of the tudor domain and translational regulation at synapsesMolecular mechanism of statin-mediated LOX-1 inhibition.JNK3 as a therapeutic target for neurodegenerative diseases.Single mutation in the linker domain confers protein flexibility and camptothecin resistance to human topoisomerase I.Conjugated eicosapentaenoic acid inhibits human topoisomerase IB with a mechanism different from camptothecin.Virtual Screening for the Development of Dual-Inhibitors Targeting Topoisomerase IB and Tyrosyl-DNA Phosphodiesterase 1.A new nitrobenzoxadiazole-based GSTP1-1 inhibitor with a previously unheard of mechanism of action and high stability.Simulative and Experimental Characterization of a pH-Dependent Clamp-like DNA Triple-Helix Nanoswitch.Synthesis and structure--activity relationship of new cytotoxic agents targeting human glutathione-S-transferases.Real-time detection of TDP1 activity using a fluorophore-quencher coupled DNA-biosensor.DNA hairpins promote temperature controlled cargo encapsulation in a truncated octahedral nanocage structure family.Influence of the single-strand linker composition on the structural/dynamical properties of a truncated octahedral DNA nano-cage family.A molecular dynamics simulation study decodes the early stage of the disassembly process abolishing the human SAMHD1 function.Deciphering the structural properties that confer stability to a DNA nanocage.Characterization of a novel CYP2C9 gene mutation and structural bioinformatic protein analysis in a warfarin hypersensitive patient.ADP/ATP mitochondrial carrier MD simulations to shed light on the structural-dynamical events that, after an additional mutation, restore the function in a pathological single mutant.Structure of nanoscale truncated octahedral DNA cages: variation of single-stranded linker regions and influence on assembly yields.Docking simulation and competitive experiments validate the interaction between the 2,5-xylidine inhibitor and Rigidoporus lignosus laccase.Molecular dynamics simulation of the antimicrobial salivary peptide histatin-5 in water and in trifluoroethanol: a microscopic description of the water destructuring effect.Spectroscopic and molecular dynamics simulation studies of the interaction of insulin with glucose.Superoxide dismutase kinetics.Flexibility in monomeric Cu,Zn superoxide dismutase detected by limited proteolysis and molecular dynamics simulation.Conservation of local electric fields in the evolution of Cu,Zn superoxide dismutase.
P50
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P50
description
hulumtuese
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Mattia Falconi
@ast
Mattia Falconi
@en
Mattia Falconi
@es
Mattia Falconi
@nl
Mattia Falconi
@sl
type
label
Mattia Falconi
@ast
Mattia Falconi
@en
Mattia Falconi
@es
Mattia Falconi
@nl
Mattia Falconi
@sl
altLabel
Mattia Falconi
@en
prefLabel
Mattia Falconi
@ast
Mattia Falconi
@en
Mattia Falconi
@es
Mattia Falconi
@nl
Mattia Falconi
@sl
P106
P21
P2456
P31
P496
0000-0002-3990-4758