APPL1 prevents pancreatic beta cell death and inflammation by dampening NFκB activation in a mouse model of type 1 diabetes.

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APPL1 prevents pancreatic beta cell death and inflammation by dampening NFκB activation in a mouse model of type 1 diabetes.

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2016 nî lūn-bûn

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2016年の論文

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2016年論文

@yue

2016年論文

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2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

@wuu

2016年论文

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2016年论文

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APPL1 prevents pancreatic beta ...... ouse model of type 1 diabetes.

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APPL1 prevents pancreatic beta ...... ouse model of type 1 diabetes.

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APPL1 prevents pancreatic beta ...... ouse model of type 1 diabetes.

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P1476

APPL1 prevents pancreatic beta ...... ouse model of type 1 diabetes.

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P2093

Aimin Xu

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Kelvin K L Wu

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Xue Jiang

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Yawen Zhou

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Zhanrui Chen

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P2860

APPL proteins link Rab5 to nuclear signal transduction via an endosomal compartment

APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function

Islet inflammation: a unifying target for diabetes treatment?

Loss-of-Function Mutations in APPL1 in Familial Diabetes Mellitus

STAT1 is a master regulator of pancreatic {beta}-cell apoptosis and islet inflammation

Interleukin-1-receptor antagonist in type 2 diabetes mellitus

Adeno-associated virus vector mediated gene transfer to pancreatic beta cells.

The unique hypusine modification of eIF5A promotes islet beta cell inflammation and dysfunction in mice.

Increased interleukin (IL)-1beta messenger ribonucleic acid expression in beta -cells of individuals with type 2 diabetes and regulation of IL-1beta in human islets by glucose and autostimulation.

Appl1 is dispensable for mouse development, and loss of Appl1 has growth factor-selective effects on Akt signaling in murine embryonic fibroblasts

P2888

s00125-016-4185-z

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464-474

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scholarly article

P356

10.1007/S00125-016-4185-Z

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P433

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P478

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Kenneth King Yip Cheng

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2016-12-23T00:00:00Z

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P6179

1012629030

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P698

28011992

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P921

type-1 diabetes