Paradoxical Effects of MLL Paralogs in MLL-Rearranged Leukemia.

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Structural and functional analysis of the DOT1L-AF10 complex reveals mechanistic insights into MLL-AF10-associated leukemogenesis.

P2860

Q52347329-38123C8D-20B2-4CA1-B45B-582241A5F7D8

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Paradoxical Effects of MLL Paralogs in MLL-Rearranged Leukemia.

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http://www.wikidata.org/entity/Q38727697

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2017 nî lūn-bûn

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2017年の論文

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2017年論文

@yue

2017年論文

@zh-hant

2017年論文

@zh-hk

2017年論文

@zh-mo

2017年論文

@zh-tw

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2017年论文

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2017年论文

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name

Paradoxical Effects of MLL Paralogs in MLL-Rearranged Leukemia.

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type

Item

label

Paradoxical Effects of MLL Paralogs in MLL-Rearranged Leukemia.

@en

prefLabel

Paradoxical Effects of MLL Paralogs in MLL-Rearranged Leukemia.

@en

P1476

Paradoxical Effects of MLL Paralogs in MLL-Rearranged Leukemia.

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P2093

Michael J Thirman

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P2860

MLL2: A new mammalian member of the trx/MLL family of genes

Altered Hox expression and segmental identity in Mll-mutant mice

MLL-AF9-induced leukemogenesis requires coexpression of the wild-type Mll allele.

AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia.

The histone 3 lysine 4 methyltransferase, Mll2, is only required briefly in development and spermatogenesis.

Targeting MLL1 H3K4 methyltransferase activity in mixed-lineage leukemia.

Unique and independent roles for MLL in adult hematopoietic stem cells and progenitors.

The histone methyltransferase activity of MLL1 is dispensable for hematopoiesis and leukemogenesis

Alterations of the CxxC domain preclude oncogenic activation of mixed-lineage leukemia 2.

P304

729-731

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P31

scholarly article

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10.1016/J.CCELL.2017.05.014

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P577

2017-06-01T00:00:00Z

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P698

28609652

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P932

5783294

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Paradoxical Effects of MLL Paralogs in MLL-Rearranged Leukemia.

about

P2860

P2860

Paradoxical Effects of MLL Paralogs in MLL-Rearranged Leukemia.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698

P932