Neratinib induces ErbB2 ubiquitylation and endocytic degradation via HSP90 dissociation in breast cancer cells.

Neratinib induces ErbB2 ubiquitylation and endocytic degradation via HSP90 dissociation in breast cancer cells.

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http://www.wikidata.org/entity/Q38738550
HER2 signaling regulates HER2 localization and membrane retention.The role of neratinib in HER2-driven breast cancer.The levels of mutant K-RAS and mutant N-RAS are rapidly reduced in a Beclin1 / ATG5 -dependent fashion by the irreversible ERBB1/2/4 inhibitor neratinib.[Neratinib + Valproate] exposure permanently reduces ERBB1 and RAS expression in 4T1 mammary tumors and enhances M1 macrophage infiltration.The irreversible ERBB1/2/4 inhibitor neratinib interacts with the BCL-2 inhibitor venetoclax to kill mammary cancer cells.The irreversible ERBB1/2/4 inhibitor neratinib interacts with the PARP1 inhibitor niraparib to kill ovarian cancer cells.Raman Micro-Spectroscopic Evidence for the Metabolism of a Tyrosine Kinase Inhibitor, Neratinib, in Cancer Cells.Posttranscriptional upregulation of HER3 by HER2 mRNA induces trastuzumab resistance in breast cancer
P2860

Neratinib induces ErbB2 ubiquitylation and endocytic degradation via HSP90 dissociation in breast cancer cells.

Item
http://www.wikidata.org/entity/Q38738550
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Neratinib induces ErbB2 ubiqui ...... iation in breast cancer cells.
@en
type
label
Neratinib induces ErbB2 ubiqui ...... iation in breast cancer cells.
@en
prefLabel
Neratinib induces ErbB2 ubiqui ...... iation in breast cancer cells.
@en
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P577
P698
P921
P356
P1433
P1476
Neratinib induces ErbB2 ubiqui ...... iation in breast cancer cells.
@en
P2093
P304
P31
P356
10.1016/J.CANLET.2016.08.026
P407
P433
P478
P577
P698
P921