Quantification of the Relative Contributions of Loss-of-function and Gain-of-function Mechanisms in TAR DNA-binding Protein 43 (TDP-43) Proteinopathies
about
RNA metabolism in neurodegenerative disease.TDP-43 and FUS en route from the nucleus to the cytoplasm.TDP-43 aggregation mirrors TDP-43 knockdown, affecting the expression levels of a common set of proteins.Protein aggregation, misfolding and consequential human neurodegenerative diseases.Acetylation-induced TDP-43 pathology is suppressed by an HSF1-dependent chaperone program.The N-terminal dimerization is required for TDP-43 splicing activity.Platelet phosphorylated TDP-43: an exploratory study for a peripheral surrogate biomarker development for Alzheimer's disease.Progranulin: a new avenue towards the understanding and treatment of neurodegenerative disease.Are Amyloid Fibrils RNA-Traps? A Molecular Dynamics Perspective.
P2860
Q33746283-324C8842-445E-4F21-A4B6-449667722EA5Q36336278-0647E64F-7986-4B4A-BB0F-E01841C0FC60Q38743891-ABF684EE-6021-49A9-9AA7-4841621DFAB8Q39097864-5B010D92-FFA5-4282-87A3-9F1FB2080103Q41061545-3773D117-0960-4DFD-B0CC-3216DDC5B56CQ41094549-1C59AB8F-D9E2-41BB-A24D-C2AFB0CCB09BQ44359436-C94760DE-94BA-4829-B4CE-6CC2A89DC316Q47623958-4E4FA394-062C-48EB-97F9-774963B24A32Q55284740-D2CB7026-FA16-4B8B-BF3D-5898B817B9E3
P2860
Quantification of the Relative Contributions of Loss-of-function and Gain-of-function Mechanisms in TAR DNA-binding Protein 43 (TDP-43) Proteinopathies
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Quantification of the Relative ...... in 43 (TDP-43) Proteinopathies
@en
type
label
Quantification of the Relative ...... in 43 (TDP-43) Proteinopathies
@en
prefLabel
Quantification of the Relative ...... in 43 (TDP-43) Proteinopathies
@en
P2093
P2860
P356
P1476
Quantification of the Relative ...... in 43 (TDP-43) Proteinopathies
@en
P2093
Claudia Capitini
Cristina Cecchi
Fabrizio Chiti
Giulia Fani
Roberta Cascella
P2860
P304
19437-19448
P356
10.1074/JBC.M116.737726
P407
P50
P577
2016-07-21T00:00:00Z